-transparent.png){kind=logo}
Seven cases of acute nonlymphoblastic leukemia showing t(8;21)(q22;q22) at diagnosis are described. Involvement of a sex chromosome was found in all patients (in six cases as a loss, and in one as a Y duplication), thus, confirming the suggestion of a correlation between these two chromosomal abnormalities. The constitutional folic acid-sensitive fragile site fra(8)(q22) was not detected, in spite of careful analysis of over 300 metaphases of cells grown in folic acid-free medium. Morphologic diagnoses and clinical aspects are briefly discussed.
Related Publications
M Sessarego, and
C Mareni, and
C Panarello, and
L Garrè, and
F Frassoni, and
P Boccaccio, and
F Ajmar
July 1986,
Cancer genetics and cytogenetics,
M Sessarego, and
C Mareni, and
C Panarello, and
L Garrè, and
F Frassoni, and
P Boccaccio, and
F Ajmar
June 1991,
The Keio journal of medicine,
M Sessarego, and
C Mareni, and
C Panarello, and
L Garrè, and
F Frassoni, and
P Boccaccio, and
F Ajmar
August 1985,
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society,
M Sessarego, and
C Mareni, and
C Panarello, and
L Garrè, and
F Frassoni, and
P Boccaccio, and
F Ajmar
March 1988,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
M Sessarego, and
C Mareni, and
C Panarello, and
L Garrè, and
F Frassoni, and
P Boccaccio, and
F Ajmar
September 1992,
Genes, chromosomes & cancer,
M Sessarego, and
C Mareni, and
C Panarello, and
L Garrè, and
F Frassoni, and
P Boccaccio, and
F Ajmar
October 2003,
Leukemia & lymphoma,
M Sessarego, and
C Mareni, and
C Panarello, and
L Garrè, and
F Frassoni, and
P Boccaccio, and
F Ajmar
June 1991,
Proceedings of the National Academy of Sciences of the United States of America,
M Sessarego, and
C Mareni, and
C Panarello, and
L Garrè, and
F Frassoni, and
P Boccaccio, and
F Ajmar
January 1990,
Nouvelle revue francaise d'hematologie,
M Sessarego, and
C Mareni, and
C Panarello, and
L Garrè, and
F Frassoni, and
P Boccaccio, and
F Ajmar
February 1999,
Cancer genetics and cytogenetics,
M Sessarego, and
C Mareni, and
C Panarello, and
L Garrè, and
F Frassoni, and
P Boccaccio, and
F Ajmar
April 1992,
International journal of hematology,
