Immune response of silver pomfret (Pampus argenteus) to Amyloodinium ocellatum infection. 2021

Youyi Zhang, and Jiabao Hu, and Yaya Li, and Man Zhang, and Kimran Jean Jacques, and Weiwei Gu, and Yibo Sun, and Jiachu Sun, and Yang Yang, and Shanliang Xu, and Yajun Wang, and Xiaojun Yan
Key Laboratory of Applied Marine Biotechnology, Ministry of Education, Ningbo University, Ningbo, China.

Amyloodinium ocellatum (AO) infection in silver pomfret (Pampus argenteus) causes extensive mortality. Insufficient information exists on the molecular immune response of silver pomfret to AO infestation, so herein we simulated the process of silver pomfret being infected by AO. Translucent trophosomes were observed on the gills of AO-infected fish. Transcriptome profiling was performed to investigate the effects of AO infection on the gill, kidney complex and spleen. Overall, 404,412,298 clean reads were obtained, assembling into 96,341 unigenes, which were annotated against public databases. In total, 2730 differentially expressed genes were detected, and few energy- and immune-related genes were further assessed using RT-qPCR. Moreover, activities of three immune-related (SOD, AKP and ACP) and three energy-related (PKM, LDH and GCK) enzymes were determined. AO infection activated the immune system and increased interleukin-1 beta and immunoglobulin M heavy chain levels. Besides, the PPAR signalling pathway was highly enriched, which played a role in improving immunity and maintaining homeostasis. AO infection also caused dyspnoea, leading to extensive lactic acid accumulation, potentially contributing towards a strong immune response in the host. Our data improved our understanding regarding the immune response mechanisms through which fish coped with parasitic infections and may help prevent high fish mortality in aquaculture.

UI MeSH Term Description Entries
D010473 Perciformes The most diversified of all fish orders and the largest vertebrate order. It includes many of the commonly known fish such as porgies, croakers, sunfishes, dolphin fish, mackerels, TUNA, etc. Bluegill,Croakers,Dolphin Fish,Porgies,Sparid Fish,Sparus,Sunfishes,Centrarchidae,Mackerels,Mahi-Mahi,Bluegills,Croaker,Fish, Sparid,Mackerel
D011529 Protozoan Infections, Animal Infections with unicellular organisms formerly members of the subkingdom Protozoa. The infections may be experimental or veterinary. Animal Protozoan Infection,Animal Protozoan Infections,Infection, Animal Protozoan,Infections, Animal Protozoan,Protozoan Infection, Animal
D004141 Dinoflagellida Flagellate EUKARYOTES, found mainly in the oceans. They are characterized by the presence of transverse and longitudinal flagella which propel the organisms in a rotating manner through the water. Dinoflagellida were formerly members of the class Phytomastigophorea under the old five kingdom paradigm. Amphidinium,Dinoflagellata,Dinophyceae,Dinophycidae,Dinophyta,Dinophytes,Gambierdiscus toxicus,Gonyaulax,Gymnodinium,Peridinium,Pyrrhophyta,Pyrrophyta,Dinoflagellates
D004417 Dyspnea Difficult or labored breathing. Orthopnea,Platypnea,Recumbent Dyspnea,Rest Dyspnea,Trepopnea,Breathlessness,Shortness of Breath,Breath Shortness,Dyspnea, Recumbent,Dyspnea, Rest,Dyspneas, Rest
D005393 Fish Diseases Diseases of freshwater, marine, hatchery or aquarium fish. This term includes diseases of both teleosts (true fish) and elasmobranchs (sharks, rays and skates). Disease, Fish,Diseases, Fish,Fish Disease
D005880 Gills Paired respiratory organs of fishes and some amphibians that are analogous to lungs. They are richly supplied with blood vessels by which oxygen and carbon dioxide are exchanged directly with the environment. Gill
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D020869 Gene Expression Profiling The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell. Gene Expression Analysis,Gene Expression Pattern Analysis,Transcript Expression Analysis,Transcriptome Profiling,Transcriptomics,mRNA Differential Display,Gene Expression Monitoring,Transcriptome Analysis,Analyses, Gene Expression,Analyses, Transcript Expression,Analyses, Transcriptome,Analysis, Gene Expression,Analysis, Transcript Expression,Analysis, Transcriptome,Differential Display, mRNA,Differential Displays, mRNA,Expression Analyses, Gene,Expression Analysis, Gene,Gene Expression Analyses,Gene Expression Monitorings,Gene Expression Profilings,Monitoring, Gene Expression,Monitorings, Gene Expression,Profiling, Gene Expression,Profiling, Transcriptome,Profilings, Gene Expression,Profilings, Transcriptome,Transcript Expression Analyses,Transcriptome Analyses,Transcriptome Profilings,mRNA Differential Displays

Related Publications

Youyi Zhang, and Jiabao Hu, and Yaya Li, and Man Zhang, and Kimran Jean Jacques, and Weiwei Gu, and Yibo Sun, and Jiachu Sun, and Yang Yang, and Shanliang Xu, and Yajun Wang, and Xiaojun Yan
January 2016, Genome,
Youyi Zhang, and Jiabao Hu, and Yaya Li, and Man Zhang, and Kimran Jean Jacques, and Weiwei Gu, and Yibo Sun, and Jiachu Sun, and Yang Yang, and Shanliang Xu, and Yajun Wang, and Xiaojun Yan
February 2024, Scientific data,
Youyi Zhang, and Jiabao Hu, and Yaya Li, and Man Zhang, and Kimran Jean Jacques, and Weiwei Gu, and Yibo Sun, and Jiachu Sun, and Yang Yang, and Shanliang Xu, and Yajun Wang, and Xiaojun Yan
June 2022, Diseases of aquatic organisms,
Youyi Zhang, and Jiabao Hu, and Yaya Li, and Man Zhang, and Kimran Jean Jacques, and Weiwei Gu, and Yibo Sun, and Jiachu Sun, and Yang Yang, and Shanliang Xu, and Yajun Wang, and Xiaojun Yan
February 2024, Animal reproduction science,
Youyi Zhang, and Jiabao Hu, and Yaya Li, and Man Zhang, and Kimran Jean Jacques, and Weiwei Gu, and Yibo Sun, and Jiachu Sun, and Yang Yang, and Shanliang Xu, and Yajun Wang, and Xiaojun Yan
December 2023, Fish & shellfish immunology,
Youyi Zhang, and Jiabao Hu, and Yaya Li, and Man Zhang, and Kimran Jean Jacques, and Weiwei Gu, and Yibo Sun, and Jiachu Sun, and Yang Yang, and Shanliang Xu, and Yajun Wang, and Xiaojun Yan
May 2004, Journal of fish diseases,
Youyi Zhang, and Jiabao Hu, and Yaya Li, and Man Zhang, and Kimran Jean Jacques, and Weiwei Gu, and Yibo Sun, and Jiachu Sun, and Yang Yang, and Shanliang Xu, and Yajun Wang, and Xiaojun Yan
September 2018, Fish & shellfish immunology,
Youyi Zhang, and Jiabao Hu, and Yaya Li, and Man Zhang, and Kimran Jean Jacques, and Weiwei Gu, and Yibo Sun, and Jiachu Sun, and Yang Yang, and Shanliang Xu, and Yajun Wang, and Xiaojun Yan
August 2020, Reproduction, fertility, and development,
Youyi Zhang, and Jiabao Hu, and Yaya Li, and Man Zhang, and Kimran Jean Jacques, and Weiwei Gu, and Yibo Sun, and Jiachu Sun, and Yang Yang, and Shanliang Xu, and Yajun Wang, and Xiaojun Yan
October 2019, Journal of fish diseases,
Youyi Zhang, and Jiabao Hu, and Yaya Li, and Man Zhang, and Kimran Jean Jacques, and Weiwei Gu, and Yibo Sun, and Jiachu Sun, and Yang Yang, and Shanliang Xu, and Yajun Wang, and Xiaojun Yan
January 2024, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology,
Copied contents to your clipboard!