Prospective randomized multicentre trial of proximal gastric vagotomy or truncal vagotomy and antrectomy for chronic duodenal ulcer: interim results. 1978

N J Dorricott, and A R Mcneish, and J Alexander-Williams, and C M Royston, and W M Cooke, and C J Spencer, and B C De Vries, and H Muller

In three centres, 222 patients (Birmingham 70, London 87 and Rotterdam 65 patients) with chronic duodenal ulcer were treated by proximal gastrict vagotomy (PGV) (116 patients) or truncal vagotomy and antrectomy (TVA) (106 patients) in a prospective randomized trial. After 1 year 5 recurrent duodenal ulcers (4.3 per cent) have been recorded in the PGV group, compared with 1 (1 per cent) in the TVA group. The reoperation rate was high in both groups-6 after PGV, usually for recurrent ulcer, and 7 after TVA, mostly for gastric retention. PGV showed a marked superiority in the number of patients with a good clinical result Visick I or II) at 1 year after operation, i.e. 82 per cent compared with 56 per cent for TVA.

UI MeSH Term Description Entries
D008297 Male Males
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D011706 Pyloric Antrum The region between the sharp indentation at the lower third of the STOMACH (incisura angularis) and the junction of the PYLORUS with the DUODENUM. Pyloric antral glands contain mucus-secreting cells and gastrin-secreting endocrine cells (G CELLS). Antrum, Pyloric,Gastric Antrum,Antrum, Gastric,Antrums, Gastric,Antrums, Pyloric,Gastric Antrums,Pyloric Antrums
D012008 Recurrence The return of a sign, symptom, or disease after a remission. Recrudescence,Relapse,Recrudescences,Recurrences,Relapses
D002908 Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). Chronic Condition,Chronic Illness,Chronically Ill,Chronic Conditions,Chronic Diseases,Chronic Illnesses,Condition, Chronic,Disease, Chronic,Illness, Chronic
D002986 Clinical Trials as Topic Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries. Clinical Trial as Topic
D004381 Duodenal Ulcer A PEPTIC ULCER located in the DUODENUM. Curling's Ulcer,Curling Ulcer,Curlings Ulcer,Duodenal Ulcers,Ulcer, Curling,Ulcer, Duodenal,Ulcers, Duodenal
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014628 Vagotomy The interruption or removal of any part of the vagus (10th cranial) nerve. Vagotomy may be performed for research or for therapeutic purposes. Vagotomies

Related Publications

N J Dorricott, and A R Mcneish, and J Alexander-Williams, and C M Royston, and W M Cooke, and C J Spencer, and B C De Vries, and H Muller
December 1983, The British journal of surgery,
N J Dorricott, and A R Mcneish, and J Alexander-Williams, and C M Royston, and W M Cooke, and C J Spencer, and B C De Vries, and H Muller
March 1983, Annals of surgery,
N J Dorricott, and A R Mcneish, and J Alexander-Williams, and C M Royston, and W M Cooke, and C J Spencer, and B C De Vries, and H Muller
April 1986, The British journal of surgery,
N J Dorricott, and A R Mcneish, and J Alexander-Williams, and C M Royston, and W M Cooke, and C J Spencer, and B C De Vries, and H Muller
May 1978, Annals of surgery,
N J Dorricott, and A R Mcneish, and J Alexander-Williams, and C M Royston, and W M Cooke, and C J Spencer, and B C De Vries, and H Muller
December 1977, Nederlands tijdschrift voor geneeskunde,
N J Dorricott, and A R Mcneish, and J Alexander-Williams, and C M Royston, and W M Cooke, and C J Spencer, and B C De Vries, and H Muller
January 1977, Acta chirurgica Scandinavica,
N J Dorricott, and A R Mcneish, and J Alexander-Williams, and C M Royston, and W M Cooke, and C J Spencer, and B C De Vries, and H Muller
October 1975, Gut,
N J Dorricott, and A R Mcneish, and J Alexander-Williams, and C M Royston, and W M Cooke, and C J Spencer, and B C De Vries, and H Muller
November 1980, Minerva medica,
N J Dorricott, and A R Mcneish, and J Alexander-Williams, and C M Royston, and W M Cooke, and C J Spencer, and B C De Vries, and H Muller
January 1981, Acta chirurgica Scandinavica,
N J Dorricott, and A R Mcneish, and J Alexander-Williams, and C M Royston, and W M Cooke, and C J Spencer, and B C De Vries, and H Muller
May 1975, British medical journal,
Copied contents to your clipboard!