-transparent.png){kind=logo}
Thirteen previously untreated patients aged 70 and above with acute nonlymphocytic leukemia were treated with aclarubicin (ACR) alone. Among 10 cases (3, acute myelocytic leukemia; 4, acute myelomonocytic leukemia; 2, acute monocytic leukemia; and one, acute erythroleukemia) in which an evaluation was possible, 5 cases (3, acute myelomonocytic leukemia; and 2, acute monocytic leukemia) obtained complete remission (CR). The CR rate was 83% in 6 patients with acute myelomonocytic leukemia or acute monocytic leukemia. The median CR duration and survival was 7.5 and 10 + months, respectively. Although side effects of the drug on digestive system such as nausea, vomiting and anorexia were observed in all patients, they were controllable by conventional treatments. The results suggest that ACR is effective for the clinical management of elderly patients with acute nonlymphocytic leukemia, especially those with acute myelomonocytic leukemia or acute monocytic leukemia.
I Takahashi, and
S Yorimitsu, and
M Hara, and
T Inagaki, and
H Nakada, and
N Sekito, and
N Hayashi, and
K Nonaka, and
E Ohmoto, and
K Uchida
January 1987,
European journal of haematology. Supplementum,
I Takahashi, and
S Yorimitsu, and
M Hara, and
T Inagaki, and
H Nakada, and
N Sekito, and
N Hayashi, and
K Nonaka, and
E Ohmoto, and
K Uchida
December 1985,
Cancer,
I Takahashi, and
S Yorimitsu, and
M Hara, and
T Inagaki, and
H Nakada, and
N Sekito, and
N Hayashi, and
K Nonaka, and
E Ohmoto, and
K Uchida
October 1984,
Cancer treatment reports,
I Takahashi, and
S Yorimitsu, and
M Hara, and
T Inagaki, and
H Nakada, and
N Sekito, and
N Hayashi, and
K Nonaka, and
E Ohmoto, and
K Uchida
June 1985,
Seminars in oncology,
I Takahashi, and
S Yorimitsu, and
M Hara, and
T Inagaki, and
H Nakada, and
N Sekito, and
N Hayashi, and
K Nonaka, and
E Ohmoto, and
K Uchida
April 1985,
Cancer,
I Takahashi, and
S Yorimitsu, and
M Hara, and
T Inagaki, and
H Nakada, and
N Sekito, and
N Hayashi, and
K Nonaka, and
E Ohmoto, and
K Uchida
December 1987,
Seminars in oncology,
I Takahashi, and
S Yorimitsu, and
M Hara, and
T Inagaki, and
H Nakada, and
N Sekito, and
N Hayashi, and
K Nonaka, and
E Ohmoto, and
K Uchida
March 1981,
Cancer genetics and cytogenetics,
I Takahashi, and
S Yorimitsu, and
M Hara, and
T Inagaki, and
H Nakada, and
N Sekito, and
N Hayashi, and
K Nonaka, and
E Ohmoto, and
K Uchida
August 1977,
Cancer,
I Takahashi, and
S Yorimitsu, and
M Hara, and
T Inagaki, and
H Nakada, and
N Sekito, and
N Hayashi, and
K Nonaka, and
E Ohmoto, and
K Uchida
June 1979,
Haematologica,
I Takahashi, and
S Yorimitsu, and
M Hara, and
T Inagaki, and
H Nakada, and
N Sekito, and
N Hayashi, and
K Nonaka, and
E Ohmoto, and
K Uchida
January 1989,
Medical and pediatric oncology,
