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Quantitative radioimmunological demonstration of carbohydrate antigen CA-50 in serum achieved a sensitivity of 62.3% for colorectal carcinoma (n = 53), of 64.7% for gastric carcinoma (n = 34), of 33.9% for lung carcinoma (n = 56), and 19.8% for lymphoproliferative diseases (n = 91). The positive results for the latter probably correspond to the immunohistological demonstration of the antigen in dendritic reticulum cells. Occasionally an increased CA-50 level in inflammatory disease presents difficulties in differential diagnosis, but it returns to normal when the inflammatory process has subsided. Methodological scatter of the CA-50 system is satisfactory, with a coefficient of variation of +/- 11%, but unsatisfactory at low values (less than or equal to 10 U/ml) and high ones (greater than or equal to 50 U/ml) with a coefficient of variation of +/- 19%. Further development with the IMRA technique may significantly reduce methodological scatter (coefficient of variation +/- 5%).
H D Bruhn, and
H Broers, and
H Euler, and
A Everding, and
A C Feller, and
J Hedderich, and
L Jostarndt, and
B Jooss, and
K H Zurborn, and
H Löffler
August 1989,
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology,
H D Bruhn, and
H Broers, and
H Euler, and
A Everding, and
A C Feller, and
J Hedderich, and
L Jostarndt, and
B Jooss, and
K H Zurborn, and
H Löffler
January 1988,
The International journal of biological markers,
H D Bruhn, and
H Broers, and
H Euler, and
A Everding, and
A C Feller, and
J Hedderich, and
L Jostarndt, and
B Jooss, and
K H Zurborn, and
H Löffler
April 1987,
International journal of cancer,
H D Bruhn, and
H Broers, and
H Euler, and
A Everding, and
A C Feller, and
J Hedderich, and
L Jostarndt, and
B Jooss, and
K H Zurborn, and
H Löffler
February 1990,
Nihon rinsho. Japanese journal of clinical medicine,
H D Bruhn, and
H Broers, and
H Euler, and
A Everding, and
A C Feller, and
J Hedderich, and
L Jostarndt, and
B Jooss, and
K H Zurborn, and
H Löffler
May 1994,
The Italian journal of gastroenterology,
H D Bruhn, and
H Broers, and
H Euler, and
A Everding, and
A C Feller, and
J Hedderich, and
L Jostarndt, and
B Jooss, and
K H Zurborn, and
H Löffler
May 1992,
British journal of cancer,
H D Bruhn, and
H Broers, and
H Euler, and
A Everding, and
A C Feller, and
J Hedderich, and
L Jostarndt, and
B Jooss, and
K H Zurborn, and
H Löffler
November 1987,
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H D Bruhn, and
H Broers, and
H Euler, and
A Everding, and
A C Feller, and
J Hedderich, and
L Jostarndt, and
B Jooss, and
K H Zurborn, and
H Löffler
May 1995,
Journal of the Medical Association of Thailand = Chotmaihet thangphaet,
H D Bruhn, and
H Broers, and
H Euler, and
A Everding, and
A C Feller, and
J Hedderich, and
L Jostarndt, and
B Jooss, and
K H Zurborn, and
H Löffler
January 1995,
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H D Bruhn, and
H Broers, and
H Euler, and
A Everding, and
A C Feller, and
J Hedderich, and
L Jostarndt, and
B Jooss, and
K H Zurborn, and
H Löffler
November 1989,
European journal of cancer & clinical oncology,
