BIOMAT Database Logo BIOMAT Database Logo

Clinical study on obstructive sleep apnea following pharyngeal flap surgery. 2021

Ning Zhao, and Zhen-Guo Liu, and Yao-Xiang Xu, and Jin Yue, and Ling-Fa Xue, and Wen-Lin Xiao
School of of Stomatology, Qingdao University, Qingdao 266555, China.

OBJECTIVE This study aims to investigate the incidence and severity of obstructive sleep apnea (OSA) in cleft patients with velopharyngeal insufficiency (VPI) after pharyngeal flap surgery (PFS) and explore the influence of operation age. METHODS A retrospective study was conducted in 82 cleft patients after PFS. The patients were divided into two groups according to their age at the time of surgery. The incidence and severity of OSA were assessed at least 1.2 years (mean 6.0 years) postoperatively by polysomnography (PSG). RESULTS The incidence rates of OSA were 20% in the adult group and 31% in the child group. No significant difference was found between the two groups (P=0.289). Patients with OSA in the adult and child groups were classified into different levels of severity (mild, moderate, severe) according to the apnea hypoventilation index (AHI). No statistically significant difference in the severity of OSA was found between the two groups (P=0.079). CONCLUSIONS Some patients still have OSA average of 6.0 years after PFS, and operation ageis unrelated to the incidence and severity of OSA.

UI MeSH Term Description Entries
D010614 Pharynx A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx). Throat,Pharynxs,Throats
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D014681 Velopharyngeal Insufficiency Failure of the SOFT PALATE to reach the posterior pharyngeal wall to close the opening between the oral and nasal cavities. Incomplete velopharyngeal closure is primarily related to surgeries (ADENOIDECTOMY; CLEFT PALATE) or an incompetent PALATOPHARYNGEAL SPHINCTER. It is characterized by hypernasal speech. Palatopharyngeal Incompetence,Inadequate Velopharyngeal Closure,Velopharyngeal Incompetence,Incompetence, Palatopharyngeal,Incompetence, Velopharyngeal,Insufficiency, Velopharyngeal,Velopharyngeal Closures, Inadequate
D017286 Polysomnography Simultaneous and continuous monitoring of several parameters during sleep to study normal and abnormal sleep. The study includes monitoring of brain waves, to assess sleep stages, and other physiological variables such as breathing, eye movements, and blood oxygen levels which exhibit a disrupted pattern with sleep disturbances. Monitoring, Sleep,Somnography,Polysomnographies,Sleep Monitoring,Somnographies
D020181 Sleep Apnea, Obstructive A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395) Obstructive Sleep Apnea,Upper Airway Resistance Sleep Apnea Syndrome,Apnea, Obstructive Sleep,OSAHS,Obstructive Sleep Apnea Syndrome,Sleep Apnea Hypopnea Syndrome,Sleep Apnea Syndrome, Obstructive,Syndrome, Obstructive Sleep Apnea,Syndrome, Sleep Apnea, Obstructive,Syndrome, Upper Airway Resistance, Sleep Apnea,Apneas, Obstructive Sleep,Obstructive Sleep Apneas,Sleep Apneas, Obstructive

Related Publications

Ning Zhao, and Zhen-Guo Liu, and Yao-Xiang Xu, and Jin Yue, and Ling-Fa Xue, and Wen-Lin Xiao
Robin sequence: obstructive sleep apnea following pharyngeal flap.
May 1997, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association,
Ning Zhao, and Zhen-Guo Liu, and Yao-Xiang Xu, and Jin Yue, and Ling-Fa Xue, and Wen-Lin Xiao
Adenoid hypertrophy causing obstructive sleep apnea in children after pharyngeal flap surgery.
December 2019, European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery,
Ning Zhao, and Zhen-Guo Liu, and Yao-Xiang Xu, and Jin Yue, and Ling-Fa Xue, and Wen-Lin Xiao
Incidence and severity of obstructive sleep apnea following pharyngeal flap surgery in patients with cleft palate.
May 2002, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association,
Ning Zhao, and Zhen-Guo Liu, and Yao-Xiang Xu, and Jin Yue, and Ling-Fa Xue, and Wen-Lin Xiao
Obstructive Sleep Apnea Following Pharyngeal Flap Surgery for Velopharyngeal Insufficiency: A Prospective Polysomnographic and Aerodynamic Study in Middle-Aged Adults.
May 2016, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association,
Ning Zhao, and Zhen-Guo Liu, and Yao-Xiang Xu, and Jin Yue, and Ling-Fa Xue, and Wen-Lin Xiao
New clinical staging for pharyngeal surgery in obstructive sleep apnea patients.
January 2014, Brazilian journal of otorhinolaryngology,
Ning Zhao, and Zhen-Guo Liu, and Yao-Xiang Xu, and Jin Yue, and Ling-Fa Xue, and Wen-Lin Xiao
Obstructive Sleep Apnea Secondary to Pharyngeal Narrowing From Horizontal Donor Site Closure During Posterior Pharyngeal Flap Surgery.
September 2020, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association,
Ning Zhao, and Zhen-Guo Liu, and Yao-Xiang Xu, and Jin Yue, and Ling-Fa Xue, and Wen-Lin Xiao
Sleep apnea following a pharyngeal flap: a feared complication.
April 1994, Plastic and reconstructive surgery,
Ning Zhao, and Zhen-Guo Liu, and Yao-Xiang Xu, and Jin Yue, and Ling-Fa Xue, and Wen-Lin Xiao
Pharyngeal fat in obstructive sleep apnea.
August 1993, The American review of respiratory disease,
Ning Zhao, and Zhen-Guo Liu, and Yao-Xiang Xu, and Jin Yue, and Ling-Fa Xue, and Wen-Lin Xiao
[Pharyngeal muscles and sleep obstructive apnea syndrome].
February 1999, Revue des maladies respiratoires,
Ning Zhao, and Zhen-Guo Liu, and Yao-Xiang Xu, and Jin Yue, and Ling-Fa Xue, and Wen-Lin Xiao
Obstructive sleep apnea and pharyngeal wall collapsibility.
June 1994, Chest,
Copied contents to your clipboard!