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Radiation-associated Angiosarcoma Presenting as Massive Pleural Effusion. 2022
Hirokazu Ogino, and
Makoto Tobiume, and
Kozo Kagawa, and
Hiroshi Kawano, and
Satoshi Sakaguchi, and
Atsuro Saijo, and
Daisuke Matsumoto, and
Hiromitsu Takizawa, and
Yuriko Morikawa, and
Yoshimi Bando, and
Hisatsugu Goto, and
Hiroshi Nokihara, and
Yasuhiko Nishioka
Department of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Japan.
A 67-year-old man was admitted to our hospital for massive pleural effusion. He had a history of mandibular gingival carcinoma treated with radiation therapy (RT). Based on the cytology findings of pleural effusion and a thoracoscopic pleural biopsy, we finally diagnosed him with radiation-associated angiosarcoma. Retrospective cell-block immunocytochemistry with pleural effusion also showed potential utility for the diagnosis. This case highlights the importance of considering the possibility of radiation-associated secondary cancer in patients with pleural effusion who have a history of RT.
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