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A panel of commercially available monoclonal antibodies and five heteroantisera were used to distinguish and subtype 138 cases of acute leukemia (AL). The immunophenotype was compared with the French-American-British (FAB) classification obtained on the cases. The immunophenotype discriminated acute myelogenous leukemia (AML) from acute lymphoblastic leukemia (ALL) and recognized cases not distinguished by cytochemistry (22% of cases), mixed lineage phenotypes (13% of cases), and cases with separate populations of lymphoblasts and myeloblasts (one case). Using the immunologic panel and derived criteria to subtype AML, correspondence of the immunophenotype to the FAB subtypes M1, M2, M4, and M5 was possible in greater than 80% of cases. A combined classification of the immunophenotype and FAB morphology/cytochemistry was devised for AML subtyping. It is recommended that immunophenotyping should be done at least in all cases with negative or inconclusive cytochemistry. At present, we suggest that until a "gold standard" for identifying leukemic subtypes is developed, the best method for typing acute leukemia is by using a combination of morphology, cytochemistry and immunophenotyping.
P B Neame, and
P Soamboonsrup, and
G P Browman, and
R M Meyer, and
A Benger, and
W E Wilson, and
I R Walker, and
N Saeed, and
J A McBride
July 1982,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
P B Neame, and
P Soamboonsrup, and
G P Browman, and
R M Meyer, and
A Benger, and
W E Wilson, and
I R Walker, and
N Saeed, and
J A McBride
October 1987,
Leukemia,
P B Neame, and
P Soamboonsrup, and
G P Browman, and
R M Meyer, and
A Benger, and
W E Wilson, and
I R Walker, and
N Saeed, and
J A McBride
October 2006,
Indian journal of pathology & microbiology,
P B Neame, and
P Soamboonsrup, and
G P Browman, and
R M Meyer, and
A Benger, and
W E Wilson, and
I R Walker, and
N Saeed, and
J A McBride
January 1989,
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion,
P B Neame, and
P Soamboonsrup, and
G P Browman, and
R M Meyer, and
A Benger, and
W E Wilson, and
I R Walker, and
N Saeed, and
J A McBride
June 1984,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
P B Neame, and
P Soamboonsrup, and
G P Browman, and
R M Meyer, and
A Benger, and
W E Wilson, and
I R Walker, and
N Saeed, and
J A McBride
July 1982,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
P B Neame, and
P Soamboonsrup, and
G P Browman, and
R M Meyer, and
A Benger, and
W E Wilson, and
I R Walker, and
N Saeed, and
J A McBride
January 1990,
The American journal of pediatric hematology/oncology,
P B Neame, and
P Soamboonsrup, and
G P Browman, and
R M Meyer, and
A Benger, and
W E Wilson, and
I R Walker, and
N Saeed, and
J A McBride
January 2004,
Annals of hematology,
P B Neame, and
P Soamboonsrup, and
G P Browman, and
R M Meyer, and
A Benger, and
W E Wilson, and
I R Walker, and
N Saeed, and
J A McBride
July 1982,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
P B Neame, and
P Soamboonsrup, and
G P Browman, and
R M Meyer, and
A Benger, and
W E Wilson, and
I R Walker, and
N Saeed, and
J A McBride
February 1987,
Rinsho byori. The Japanese journal of clinical pathology,
