Vascular Behcet's Disease Preceded by Fever of Unknown Origin: Usefulness of Ultrasonography for the Detection of Large-Vessel Vasculitis. 2021

Haruki Matsumoto, and Makiko Yashiro-Furuya, and Yuya Fujita, and Tomoyuki Asano, and Tatsuhiko Mori, and Shuzo Sato, and Jumpei Temmoku, and Naoki Matsuoka, and Hiroshi Watanabe, and Eiji Suzuki, and Kiyoshi Migita
Department of Rheumatology, Fukushima Medical University School of Medicine.

Behcet's disease is a systemic vasculitis characterized by oral and genital ulcers, erythema nodosum, and ocular involvement. Fever of unknown origin is a relatively rare event in Behcet's disease. We present the case of a 17-year-old male patient who suffered from prolonged fever for two months. The patient tested positive for HLA-B52 and levels of acute phase reactants were elevated. He complained of sore throat and neck pain that were evaluated by cervical ultrasonography, which revealed thickening of the carotid arterial wall and narrowing of the vessel lumen. The patient was diagnosed with vascular Behcet's disease and treated with glucocorticoid, which improved the clinical symptoms and thickening of the carotid arterial wall as detected by color duplex ultrasonography. Since vascular Behcet's disease may lead to morbidity and mortality, we suggest the early use of ultrasonography to help detect medium/large-vessel vasculitis. Prolonged fever in patients with Behcet's disease should be promptly evaluated for vascular involvement.

UI MeSH Term Description Entries
D008297 Male Males
D005335 Fever of Unknown Origin Fever in which the etiology cannot be ascertained. Unknown Origin Fever,Unknown Origin Fevers
D005938 Glucocorticoids A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system. Glucocorticoid,Glucocorticoid Effect,Glucorticoid Effects,Effect, Glucocorticoid,Effects, Glucorticoid
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D001528 Behcet Syndrome Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well. Behcet Disease,Behcet's Disease,Behcet's Syndrome,Triple-Symptom Complex,Adamantiades-Behcet Disease,Behcet Triple Symptom Complex,Behçet Disease,Old Silk Route Disease,Triple Symptom Complex,Adamantiades Behcet Disease,Adamantiades-Behcet Diseases,Behçet Diseases,Symptom Complex, Triple,Triple Symptom Complices
D014463 Ultrasonography The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz. Echography,Echotomography,Echotomography, Computer,Sonography, Medical,Tomography, Ultrasonic,Ultrasonic Diagnosis,Ultrasonic Imaging,Ultrasonographic Imaging,Computer Echotomography,Diagnosis, Ultrasonic,Diagnostic Ultrasound,Ultrasonic Tomography,Ultrasound Imaging,Diagnoses, Ultrasonic,Diagnostic Ultrasounds,Imaging, Ultrasonic,Imaging, Ultrasonographic,Imaging, Ultrasound,Imagings, Ultrasonographic,Imagings, Ultrasound,Medical Sonography,Ultrasonic Diagnoses,Ultrasonographic Imagings,Ultrasound, Diagnostic,Ultrasounds, Diagnostic
D014657 Vasculitis Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body. Angiitis,Angiitides,Vasculitides

Related Publications

Haruki Matsumoto, and Makiko Yashiro-Furuya, and Yuya Fujita, and Tomoyuki Asano, and Tatsuhiko Mori, and Shuzo Sato, and Jumpei Temmoku, and Naoki Matsuoka, and Hiroshi Watanabe, and Eiji Suzuki, and Kiyoshi Migita
September 2013, Rheumatology international,
Haruki Matsumoto, and Makiko Yashiro-Furuya, and Yuya Fujita, and Tomoyuki Asano, and Tatsuhiko Mori, and Shuzo Sato, and Jumpei Temmoku, and Naoki Matsuoka, and Hiroshi Watanabe, and Eiji Suzuki, and Kiyoshi Migita
July 1985, Archives of internal medicine,
Haruki Matsumoto, and Makiko Yashiro-Furuya, and Yuya Fujita, and Tomoyuki Asano, and Tatsuhiko Mori, and Shuzo Sato, and Jumpei Temmoku, and Naoki Matsuoka, and Hiroshi Watanabe, and Eiji Suzuki, and Kiyoshi Migita
June 2010, Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases,
Haruki Matsumoto, and Makiko Yashiro-Furuya, and Yuya Fujita, and Tomoyuki Asano, and Tatsuhiko Mori, and Shuzo Sato, and Jumpei Temmoku, and Naoki Matsuoka, and Hiroshi Watanabe, and Eiji Suzuki, and Kiyoshi Migita
January 2009, Acta medica portuguesa,
Haruki Matsumoto, and Makiko Yashiro-Furuya, and Yuya Fujita, and Tomoyuki Asano, and Tatsuhiko Mori, and Shuzo Sato, and Jumpei Temmoku, and Naoki Matsuoka, and Hiroshi Watanabe, and Eiji Suzuki, and Kiyoshi Migita
December 2001, Journal of Nippon Medical School = Nippon Ika Daigaku zasshi,
Haruki Matsumoto, and Makiko Yashiro-Furuya, and Yuya Fujita, and Tomoyuki Asano, and Tatsuhiko Mori, and Shuzo Sato, and Jumpei Temmoku, and Naoki Matsuoka, and Hiroshi Watanabe, and Eiji Suzuki, and Kiyoshi Migita
February 2009, The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...,
Haruki Matsumoto, and Makiko Yashiro-Furuya, and Yuya Fujita, and Tomoyuki Asano, and Tatsuhiko Mori, and Shuzo Sato, and Jumpei Temmoku, and Naoki Matsuoka, and Hiroshi Watanabe, and Eiji Suzuki, and Kiyoshi Migita
August 2020, Rheumatology (Oxford, England),
Haruki Matsumoto, and Makiko Yashiro-Furuya, and Yuya Fujita, and Tomoyuki Asano, and Tatsuhiko Mori, and Shuzo Sato, and Jumpei Temmoku, and Naoki Matsuoka, and Hiroshi Watanabe, and Eiji Suzuki, and Kiyoshi Migita
June 2008, Klinicka mikrobiologie a infekcni lekarstvi,
Haruki Matsumoto, and Makiko Yashiro-Furuya, and Yuya Fujita, and Tomoyuki Asano, and Tatsuhiko Mori, and Shuzo Sato, and Jumpei Temmoku, and Naoki Matsuoka, and Hiroshi Watanabe, and Eiji Suzuki, and Kiyoshi Migita
January 2018, BMJ case reports,
Haruki Matsumoto, and Makiko Yashiro-Furuya, and Yuya Fujita, and Tomoyuki Asano, and Tatsuhiko Mori, and Shuzo Sato, and Jumpei Temmoku, and Naoki Matsuoka, and Hiroshi Watanabe, and Eiji Suzuki, and Kiyoshi Migita
January 2006, Scandinavian journal of infectious diseases,
Copied contents to your clipboard!