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The divergent, muscle-specific allele of the chicken calmodulin gene contains no intervening sequences and apparently was produced by a reverse transcriptase-mediated event. The nucleotide and deduced amino acid sequences of this gene were compared with nucleotide and amino acid sequence data of other known calmodulin genes in order to investigate its evolutionary history. These comparisons, as well as the CpG dinucleotide content, support the conclusion that this highly divergent chicken calmodulin gene did not exist for any significant period of times as a pseudogene and suggest plausible alternative genetic histories. The most parsimonious history involves the viral import of a very old foreign gene of high CpG content.
K D Gruskin, and
T F Smith, and
M Goodman
December 1980,
Nature,
K D Gruskin, and
T F Smith, and
M Goodman
December 1982,
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K D Gruskin, and
T F Smith, and
M Goodman
November 1983,
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K D Gruskin, and
T F Smith, and
M Goodman
December 1980,
Nucleic acids research,
K D Gruskin, and
T F Smith, and
M Goodman
June 1982,
Nature,
K D Gruskin, and
T F Smith, and
M Goodman
May 1980,
Proceedings of the National Academy of Sciences of the United States of America,
K D Gruskin, and
T F Smith, and
M Goodman
January 1979,
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K D Gruskin, and
T F Smith, and
M Goodman
June 1992,
Proceedings of the National Academy of Sciences of the United States of America,
K D Gruskin, and
T F Smith, and
M Goodman
July 1978,
Nature,
K D Gruskin, and
T F Smith, and
M Goodman
December 1979,
Proceedings of the National Academy of Sciences of the United States of America,
