-transparent.png){kind=logo}
Red blood cell (RBC) and plasma catecholamine content were determined by high performance liquid chromatography in 18 patients suspected of having phaeochromocytoma on the basis of clinical manifestations, especially hypertension and laboratory findings. Eight normotensive health individuals served as controls. The fivne patients with tumours had strikingly greater RBC catecholamine concentrations (C) than in plasma and reached CRBS/Cplasma ratios approximating 5, significantly different from the ratios in controls and in hypertensive patients without tumours. One tumour patient had a normal RBC catecholamine content as well as repeatedly normal plasma and urinary catecholamine levels. The other 12 patients, who had no ++tumours, had only slight elevations in plasma and RBC catecholamine levels. There is an accelerated uptake of catecholamines against a concentration gradient by the RBC in phaeochromocytoma, which indicates that RBC play a major role in the clearance of catecholamines after they are secreted into circulation.
N O Atuk, and
S Turner, and
R Carey, and
C Ayers
January 1972,
Clinical pharmacology and therapeutics,
N O Atuk, and
S Turner, and
R Carey, and
C Ayers
January 2005,
Clinical nuclear medicine,
N O Atuk, and
S Turner, and
R Carey, and
C Ayers
July 1975,
Experimental cell research,
N O Atuk, and
S Turner, and
R Carey, and
C Ayers
December 1986,
Toxicology,
N O Atuk, and
S Turner, and
R Carey, and
C Ayers
August 1994,
Clinical autonomic research : official journal of the Clinical Autonomic Research Society,
N O Atuk, and
S Turner, and
R Carey, and
C Ayers
January 1998,
The Analyst,
N O Atuk, and
S Turner, and
R Carey, and
C Ayers
June 1964,
Biochemical pharmacology,
N O Atuk, and
S Turner, and
R Carey, and
C Ayers
November 1976,
Lancet (London, England),
N O Atuk, and
S Turner, and
R Carey, and
C Ayers
October 1990,
The Biochemical journal,
N O Atuk, and
S Turner, and
R Carey, and
C Ayers
January 1989,
Indian journal of experimental biology,
