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Temporary threshold shift induced by noise exposure and moderate salicylate intake. 1986

F Lindgren, and A Axelsson

Temporary threshold shift was examined in 10 voluntary subjects who were exposed on 5 occasions to noise only and on 5 additional occasions to noise after intake of 1 g acetylsalicylic acid (ASA). The results showed no evidence that moderate doses of ASA potentiate temporary threshold shift. Subjects tested before and 1 hour after intake of ASA showed hearing improvement after intake of ASA. This threshold shift was confirmed, by a control trial, to depend on a practice effect rather than on the ASA.

UI MeSH Term Description Entries
D008297 Male Males
D009622 Noise Any sound which is unwanted or interferes with HEARING other sounds. Noise Pollution,Noises,Pollution, Noise
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D001241 Aspirin The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5) Acetylsalicylic Acid,2-(Acetyloxy)benzoic Acid,Acetysal,Acylpyrin,Aloxiprimum,Colfarit,Dispril,Easprin,Ecotrin,Endosprin,Magnecyl,Micristin,Polopirin,Polopiryna,Solprin,Solupsan,Zorprin,Acid, Acetylsalicylic
D001305 Auditory Fatigue Loss of sensitivity to sounds as a result of auditory stimulation, manifesting as a temporary shift in auditory threshold. The temporary threshold shift, TTS, is expressed in decibels. Fatigue, Auditory,Temporary Threshold Shift, Auditory,Auditory Fatigues,Fatigues, Auditory

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