Biomaterial Database

Serious corneal complications associated with extended-wear soft contact lenses for myopia. 1986

G P Spindel, and H D Perry

Three patients wearing extended wear contact lenses for correction of myopia presented with severe corneal complications including corneal ulcers and corneal infiltrates. All cases were assembled over a four-month period, reflecting the alarming rise in severe corneal complications related to increased usage of these lenses. We feel indiscriminate dispensing and lack of proper follow-up care are primary contributing factors in the near epidemic rise in severe corneal problems related to this usage. Two of our three patients had significant permanent visual loss following resolution of their contact lens problems.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009216	Myopia	A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.	Nearsightedness,Myopias,Nearsightednesses
D003262	Contact Lenses, Extended-Wear	Hydrophilic contact lenses worn for an extended period or permanently.	Contact Lens, Extended-Wear,Contact Lens, Extended Wear,Contact Lenses, Extended Wear,Extended-Wear Contact Lens,Extended-Wear Contact Lenses,Lens, Extended-Wear Contact,Lenses, Extended-Wear Contact
D003263	Contact Lenses, Hydrophilic	Soft, supple contact lenses made of plastic polymers which interact readily with water molecules. Many types are available, including continuous and extended-wear versions, which are gas-permeable and easily sterilized.	Lenses, Contact, Hydrophilic,Soft Contact Lenses,Hydrophilic Contact Lens,Soft Contact Lens,Contact Lens, Hydrophilic,Contact Lens, Soft,Contact Lenses, Soft,Hydrophilic Contact Lenses,Lens, Hydrophilic Contact,Lens, Soft Contact,Lenses, Hydrophilic Contact,Lenses, Soft Contact
D003316	Corneal Diseases	Diseases of the cornea.	Corneal Disease,Disease, Corneal,Diseases, Corneal
D003320	Corneal Ulcer	Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.	Keratitis, Ulcerative,Keratitides, Ulcerative,Ulcer, Corneal,Ulcerative Keratitides,Ulcerative Keratitis
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths