The effect of age on blood pressure and heart rate variability in hypertension. 1986

M Brennan, and E O'Brien, and K O'Malley

There is confusion in the literature as to the effect of ageing on blood pressure variability. The lack of consistency in reports probably reflects differences in blood pressure measurement techniques and in the choice of statistics used to describe variability. We studied 16 hypertensives (clinical blood pressure greater than 140/90 mmHg on 3 occasions) over 60 (67 +/- 5.5 years) and 16 under 60 years of age (44 +/- 8.9 years) using the Remler M 2000 ambulatory system to measure blood pressure and heart rate every 30 min during the awake hours of the day. Mean +/- s.e.m. blood pressure and heart rate for the elderly was 168 +/- 2.5/95 +/- 1.0 mmHg and 72 +/- 1.5 beats/min, corresponding values for the young being 162 +/- 5.3/103 +/- 2.1 and 78 +/- 2.5. Four statistics of variability were used: standard deviation, coefficient of variation, range and mean hourly change. Differences between old and young were found only for the range of systolic and diastolic blood pressure which was lower in the elderly (52 +/- 3.9/32 +/- 2.4 versus 67 +/- 5.2/46 +/- 4.8 mmHg, both P less than 0.05) and mean hourly change of heart rate (P less than 0.05). The standard deviation of heart rate was negatively correlated with age (r = -0.37; P less than 0.05). Only the systolic and diastolic blood pressure ranges were found to differ with age; the more rigorous tests of variability, standard deviation and coefficient of variation, were not changed. These data show that in hypertensives of different age but with roughly comparable blood pressure levels, variability of blood pressure is not consistently related to age.(ABSTRACT TRUNCATED AT 250 WORDS)

UI MeSH Term Description Entries
D006973 Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. Blood Pressure, High,Blood Pressures, High,High Blood Pressure,High Blood Pressures
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D001794 Blood Pressure PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS. Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D006339 Heart Rate The number of times the HEART VENTRICLES contract per unit of time, usually per minute. Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000375 Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. Senescence,Aging, Biological,Biological Aging

Related Publications

M Brennan, and E O'Brien, and K O'Malley
April 1987, The American journal of cardiology,
M Brennan, and E O'Brien, and K O'Malley
October 2000, Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering,
M Brennan, and E O'Brien, and K O'Malley
June 1986, Journal of hypertension,
M Brennan, and E O'Brien, and K O'Malley
July 2000, Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology,
M Brennan, and E O'Brien, and K O'Malley
January 2006, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban,
M Brennan, and E O'Brien, and K O'Malley
April 2005, Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi,
M Brennan, and E O'Brien, and K O'Malley
January 2001, IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society,
M Brennan, and E O'Brien, and K O'Malley
December 2003, Hypertension (Dallas, Tex. : 1979),
M Brennan, and E O'Brien, and K O'Malley
January 2012, Hypertension in pregnancy,
Copied contents to your clipboard!