Observation on the Efficacy of Shouhui Tongbian Capsule in the Treatment of Functional Constipation and Study on Its Regulatory Effect on Intestinal Flora. 2021

Hongxi Zhang, and Bao Han, and Zhiyun Zhang, and Zhenguo Tian, and Yongduo Yu
Department of Anorectal, The Third Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110005, Liaoning, China.

Functional constipation is relatively common in both adults and children, exhibiting similar symptoms. However, there are significant differences in the epidemiology, symptomatology, pathophysiology, diagnostic tests, and treatment management of functional constipation by age. The treatment of functional constipation is generally based on lifestyle interventions, pelvic floor interventions, and pharmacotherapy. Pharmacological treatment is popular as the most direct and effective modality, especially the herbal preparations (e.g., Shouhui Tongbian capsule), which are popular for their lower toxic side effects and less physiological reactions. In our clinical study, patients with functional constipation who took Shouhui Tongbian capsules for a longer period of time showed significantly better improvement than those who took them for a shorter period of time (P < 0.001). Relative to the duration of the disease, the improvement effect was higher in patients with short duration of the disease than in patients with long duration of the disease (P < 0.001). What's more, Shouhui Tongbian capsule had a regulating effect on intestinal flora, and the regulating effect was stronger in patients with a shorter disease duration.

UI MeSH Term Description Entries
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D003248 Constipation Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. Colonic Inertia,Dyschezia
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000069196 Gastrointestinal Microbiome All of the microbial organisms that naturally exist within the GASTROINTESTINAL TRACT. Enteric Bacteria,Gastric Microbiome,Gastrointestinal Flora,Gastrointestinal Microbial Community,Gastrointestinal Microbiota,Gastrointestinal Microflora,Gut Flora,Gut Microbiome,Gut Microbiota,Gut Microflora,Intestinal Flora,Intestinal Microbiome,Intestinal Microbiota,Intestinal Microflora,Bacteria, Enteric,Flora, Gastrointestinal,Flora, Gut,Flora, Intestinal,Gastric Microbiomes,Gastrointestinal Microbial Communities,Gastrointestinal Microbiomes,Gastrointestinal Microbiotas,Gut Microbiomes,Gut Microbiotas,Intestinal Microbiomes,Intestinal Microbiotas,Microbial Community, Gastrointestinal,Microbiome, Gastric,Microbiome, Gastrointestinal,Microbiome, Gut,Microbiome, Intestinal,Microbiota, Gastrointestinal,Microbiota, Gut,Microbiota, Intestinal,Microflora, Gastrointestinal,Microflora, Gut,Microflora, Intestinal
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

Hongxi Zhang, and Bao Han, and Zhiyun Zhang, and Zhenguo Tian, and Yongduo Yu
January 2023, Journal of healthcare engineering,
Hongxi Zhang, and Bao Han, and Zhiyun Zhang, and Zhenguo Tian, and Yongduo Yu
April 2024, Chinese herbal medicines,
Hongxi Zhang, and Bao Han, and Zhiyun Zhang, and Zhenguo Tian, and Yongduo Yu
October 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,
Hongxi Zhang, and Bao Han, and Zhiyun Zhang, and Zhenguo Tian, and Yongduo Yu
February 2021, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
Hongxi Zhang, and Bao Han, and Zhiyun Zhang, and Zhenguo Tian, and Yongduo Yu
January 2023, Phytomedicine : international journal of phytotherapy and phytopharmacology,
Hongxi Zhang, and Bao Han, and Zhiyun Zhang, and Zhenguo Tian, and Yongduo Yu
November 2022, Journal of ethnopharmacology,
Hongxi Zhang, and Bao Han, and Zhiyun Zhang, and Zhenguo Tian, and Yongduo Yu
February 2021, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
Hongxi Zhang, and Bao Han, and Zhiyun Zhang, and Zhenguo Tian, and Yongduo Yu
February 2021, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
Hongxi Zhang, and Bao Han, and Zhiyun Zhang, and Zhenguo Tian, and Yongduo Yu
February 2021, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
Copied contents to your clipboard!