Biomaterial Database

Lipopolysaccharide (endotoxin) from individual periodontally involved teeth. 1987

M Maidwell-Smith, and M Wilson, and J B Kieser

Department of Periodontology, Eastman Dental Hospirtal, London, UK.

The amount of lipopolysaccharide (LPS) in the root surface-associated material from individual periodontally-involved teeth has been determined. LPS was found in the surface material from all of the teeth and the amount present ranged from 19-394 ng/tooth. No significant correlation was found between the amount of LPS extracted from a particular tooth and the mean pocket depth associated with the tooth. However, a weak correlation (rs = +0.461, 0.05 greater than p greater than 0.01) was found between the amount of LPS and the % loss of attachment.

UI	MeSH Term	Description	Entries
D008070	Lipopolysaccharides	Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)	Lipopolysaccharide,Lipoglycans
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010510	Periodontal Diseases	Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.	Parodontosis,Pyorrhea Alveolaris,Disease, Periodontal,Diseases, Periodontal,Parodontoses,Periodontal Disease
D010512	Periodontal Index	A numerical rating scale for classifying the periodontal status of a person or population with a single figure which takes into consideration prevalence as well as severity of the condition. It is based upon probe measurement of periodontal pockets and on gingival tissue status.	Bleeding on Probing, Gingival,CPITN,Community Periodontal Index of Treatment Needs,Gingival Bleeding on Probing,Gingival Index,Gingival Indexes,Periodontal Indexes,Gingival Indices,Index, Gingival,Index, Periodontal,Indexes, Gingival,Indexes, Periodontal,Indices, Gingival,Indices, Periodontal,Periodontal Indices
D010514	Periodontal Pocket	An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.	Pocket, Periodontal,Periodontal Pockets,Pockets, Periodontal
D003741	Dental Deposits	Accumulations of microflora that lead to pathological plaque and calculus which cause PERIODONTAL DISEASES. It can be considered a type of BIOFILMS. It is subtly distinguished from the protective DENTAL PELLICLE.	Materia Alba,Dental Deposit,Deposit, Dental,Deposits, Dental
D004731	Endotoxins	Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.	Endotoxin
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D014092	Tooth Root	The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)	Root, Tooth,Roots, Tooth,Tooth Roots