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Right Ventricular Mass 12 Years after Osteosarcoma: Multimodality Imaging with Pathologic Correlation. 2021
Badr Bannan, and
Huda S Ismail, and
Faisal M Alabdulkarim, and
Bradley Sarak, and
Tushar Vora, and
Laura Jimenez-Juan, and
Abha Gupta, and
Andrew T Yan, and
Danny Marcuzzi, and
Géraldine Ong, and
David A Latter, and
Elsie T Nguyen, and
Michael A Seidman, and
Robert J Cusimano, and
Djeven P Deva
Department of Medical Imaging (B.B., H.S.I., F.M.A., L.J.J., A.T.Y., D.M., D.P.D.), Division of Cardiology (B.S., A.T.Y., G.O.), Keenan Research Centre, Li Ka Shing Knowledge Institute (L.J.J., A.T.Y., D.P.D.), Department of Cardiac Surgery (D.A.L.), and Department of Echocardiography (B.S., G.O.), St. Michael's Hospital, University of Toronto, 30 Bond St, Toronto, ON, Canada, M5B 1W8; Division of Medical Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada (T.V., A.G.); Department of Medicine, University of Toronto, Toronto, Canada (A.T.Y., G.O.); Department of Medical Imaging (E.T.N.), Peter Munk Cardiac Centre (E.T.N.), Laboratory Medicine Program, University Health Network (M.A.S.), Department of Laboratory Medicine and Pathobiology (M.A.S.), and Department of Cardiovascular Surgery (R.J.C.), Toronto General Hospital, University of Toronto, Toronto, Canada.
The authors report a 27-year-old woman with a remote left femoral osteosarcoma and amputation above the left knee who presented with a large right ventricular mass. Initial evaluation with thoracic CT was inconclusive regarding thrombus versus tumor, but metastatic osteosarcoma was suggested by findings at transthoracic echocardiography, cardiac CT, and cardiac MRI. The patient underwent tumor debulking, and osteosarcoma was confirmed with pathologic examination. She responded to chemotherapy, which resulted in reduction in size of the residual right ventricular tumor and of a few pulmonary metastases. Following induction chemotherapy, patient remains well undergoing maintenance therapy with an oral tyrosine kinase inhibitor. Keywords: CT, Echocardiography, MR Imaging, Intraoperative, Cardiac, Heart, Right Ventricle, Imaging Sequences, Metastases, Oncology Supplemental material is available for this article. © RSNA, 2021.
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