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Leave no sister behind. 2021

Michael A Hadders, and Susanne M A Lens
Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

Recent work published in Cell Reports and Developmental Cell from Sen et al., Orr et al., and Papini et al., demonstrates that midzone-based Aurora B resolves chromosome segregation errors during anaphase.

UI MeSH Term Description Entries
D000705 Anaphase The phase of cell nucleus division following METAPHASE, in which the CHROMATIDS separate and migrate to opposite poles of the spindle. Anaphases
D020090 Chromosome Segregation The orderly segregation of CHROMOSOMES during MEIOSIS or MITOSIS. Chromosome Segregations,Segregation, Chromosome,Segregations, Chromosome
D064107 Aurora Kinase B An aurora kinase that is a component of the chromosomal passenger protein complex and is involved in the regulation of MITOSIS. It mediates proper CHROMOSOME SEGREGATION and contractile ring function during CYTOKINESIS. Aurora B Kinase,Aurora B Kinases,Aurora Kinases B,Aurora-Related Kinase 2,Serine-Threonine Protein Kinase 12,Aurora Related Kinase 2,B Kinase, Aurora,Kinase, Aurora B,Serine Threonine Protein Kinase 12

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