There is plenty bibliography about the impact of the coronavirus disease 2019 (COVID-19) pandemic on the mental and social health of children, adolescents, and youth. A very high percentage of this population developed emotional symptoms and their levels of anxiety, depression, and suicidal ideation increased considerably. The adults who were responsible for generating a support network were impacted and suffered emotional symptoms and job and economic uncertainty. In many children, without a supportive context, exposure to adverse experiences increased, so the pandemic may be considered an adverse experience itself. The future effect of such unfavorable experience on childhood and how family and social support may help to reduce stress through the development of resilience were reviewed. As citizens and health care providers, our responsibility is to reflect, discuss, and develop strategies to mitigate such damage that may have severe consequences on the mental and physical health of children and adults.