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A study was done to test whether ovulatory follicles destined to form subfunctional corpora lutea differed from normal ovulatory follicles in steroidogenic function. Twenty-five ewes were treated with prostaglandin F2 alpha on d 11 of the estrous cycle, then unilaterally ovariectomized before (n = 13) or after (n = 12) the surge of luteinizing hormone (LH) at the induced estrus to collect "control" follicles, which would have produced normal corpora lutea. In 15 ewes, the second ovary was removed 63 to 84 h later to collect "treated" follicles before (n = 7) or after (n = 8) the second expected surge of LH. Five ewes (control) were allowed to ovulate from the remaining ovary at first estrus and another five (treated) at the second estrus (3 to 4 d later). Treated ewes had lower serum progesterone than control ewes during the ensuing cycle (P less than .05). Treated follicles contained less estradiol in the theca (4.4 +/- .6 vs 10.0 +/- 2.5 ng; P less than .05), less androstenedione (.1 +/- .1 vs 1.0 +/- .2 ng) and estradiol (.5 +/- .1 vs 2.9 +/- 2.2 ng) in the granulosa (P less than .05) and less progesterone in the follicular fluid (.8 +/- .4 vs 3.3 +/- .8 ng; P less than .05) than control follicles, when removed before the surge of LH. Follicles removed after the surge of LH did not differ. In conclusion, ovulatory follicles with low steroidogenic function became corpora lutea that secreted lower-than-normal quantities of progesterone.
L M White, and
D H Keisler, and
R A Dailey, and
E K Inskeep
December 1970,
Endocrinology,
L M White, and
D H Keisler, and
R A Dailey, and
E K Inskeep
January 1989,
Journal of reproduction and fertility,
L M White, and
D H Keisler, and
R A Dailey, and
E K Inskeep
January 1971,
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L M White, and
D H Keisler, and
R A Dailey, and
E K Inskeep
January 1974,
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L M White, and
D H Keisler, and
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January 1995,
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L M White, and
D H Keisler, and
R A Dailey, and
E K Inskeep
November 1978,
Journal of reproduction and fertility,
L M White, and
D H Keisler, and
R A Dailey, and
E K Inskeep
August 2010,
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L M White, and
D H Keisler, and
R A Dailey, and
E K Inskeep
August 1988,
The Veterinary clinics of North America. Equine practice,
L M White, and
D H Keisler, and
R A Dailey, and
E K Inskeep
February 1995,
Endocrinology,
L M White, and
D H Keisler, and
R A Dailey, and
E K Inskeep
September 1944,
Science (New York, N.Y.),
