Biomaterial Database

Effects of NaF and SnF2 on growth, acid and glucan production of several oral streptococci. 1987

R L Zameck, and N Tinanoff

Department of Pediatric Dentistry, School of Dental Medicine, University of Connecticut Health Center, Farmington 06032.

The effects of low concentrations of these fluorides on Streptococcus sobrinus, Streptococcus mutans, Streptococcus salivarius, Streptococcus mitior and Streptococcus sanguis were investigated. Without fluoride, mutans streptococci (Strep. mutans and Strep. sobrinus) produced more acid than the other strains; both fluorides reduced acid production in all strains. NaF had little effect on growth; SnF2 decreased growth in all strains, most evidently in the Strep. mutans. In all growth conditions, Strep. sobrinus produced the most alkali-soluble glucan. Both fluorides enhanced alkali-soluble glucan production in mutans streptococci while only SnF2 enhanced this in the other streptococci.

UI	MeSH Term	Description	Entries
D004269	DNA, Bacterial	Deoxyribonucleic acid that makes up the genetic material of bacteria.	Bacterial DNA
D005459	Fluorides	Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices.	Fluoride
D005936	Glucans	Polysaccharides composed of repeating glucose units. They can consist of branched or unbranched chains in any linkages.	Glucan,Polyglucose,Polyglucoses,Glucan (BO),Glucose Polymer,Polycose,Polymer, Glucose
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012969	Sodium Fluoride	A source of inorganic fluoride which is used topically to prevent dental caries.	Fluoristat,Ossin,Zymafluor,Fluoride, Sodium,Fluorides, Sodium,Fluoristats,Ossins,Sodium Fluorides,Zymafluors
D013291	Streptococcus	A genus of gram-positive, coccoid bacteria whose organisms occur in pairs or chains. No endospores are produced. Many species exist as commensals or parasites on man or animals with some being highly pathogenic. A few species are saprophytes and occur in the natural environment.
D013295	Streptococcus mutans	A polysaccharide-producing species of STREPTOCOCCUS isolated from human dental plaque.
D014002	Tin Fluorides	Inorganic fluorides of tin. They include both stannic fluoride (tin tetrafluoride) and stannous fluoride (tin difluoride). The latter is used in the prevention of dental caries.	Stannic Fluoride,Stannous Fluoride,Tin Difluoride,Tin Tetrafluoride,Cav-X,Floran,Fluoristan,Gel-Kam,Gel-Tin,Omnii-Gel,Omnii-Med,Stanimax,Difluoride, Tin,Difluorides, Tin,Florans,Fluoride, Stannic,Fluoride, Stannous,Fluoride, Tin,Fluorides, Stannic,Fluorides, Stannous,Fluorides, Tin,Fluoristans,Stanimaxs,Stannic Fluorides,Stannous Fluorides,Tetrafluoride, Tin,Tetrafluorides, Tin,Tin Difluorides,Tin Fluoride,Tin Tetrafluorides