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Italian Children Exposure to Bisphenol A: Biomonitoring Data from the LIFE PERSUADED Project. 2021
Sabrina Tait, and
Fabrizia Carli, and
Luca Busani, and
Demetrio Ciociaro, and
Veronica Della Latta, and
Annalisa Deodati, and
Enrica Fabbrizi, and
Anna Paola Pala, and
Francesca Maranghi, and
Roberta Tassinari, and
Giacomo Toffol, and
Stefano Cianfarani, and
Amalia Gastaldelli, and
Cinzia La Rocca, and
Life Persuaded Project Group
Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
A human biomonitoring (HBM) study on bisphenol A (BPA) in Italian children and adolescents was performed within the LIFE PERSUADED project, considering the residing areas, sex and age. The median urinary BPA level was 7.02 µg/L, with children living in the South of Italy or in urban areas having higher levels than those residing in the North or in rural areas. Children aged 4-6 years had higher BPA levels than those aged 7-10 and 11-14 years, but no differences were detected between sexes. The exposure in Italian children was higher compared to children from other countries, but lower than the HBM guidance value (135 µg/L). The estimated daily intake was 0.17 μg/kg body weight (bw) per day, about 24-fold below the temporary Tolerable Daily Intake of 4 μg/kg bw per day established by the European Food Safety Authority. However, this threshold was exceeded in 1.44% of the enrolled children, raising concern about the overall exposure of Italian young population.
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