Biomaterial Database

[Clinical characteristics of 288 cases of pathologically confirmed benign pulmonary nodules post-surgery]. 2021

S X Zhang, and G C Shi

Department of Respiratory and Critical Care Medicine, Ruijin Hospital,Shanghai Jiaotong University School of Medicine;Institute of Respiratory Diseases, Shanghai Jiaotong University School of Medicine,Shanghai 200025,China.

Objective: To analyze retrospectively the clinical characteristics of pathologically confirmed benign pulmonary nodules post-surgery, and therefore to provide evidence for the diagnosis of benign pulmonary nodules. Methods: 288 cases of pulmonary nodules were selected in the Ruijin Hospital from 1st January 2017 to 31st October 2019. All the lesions of these patients were confirmed by surgery and had definite pathological diagnosis. The clinical data were collected, including demography, clinical data, radiological features. Features that indicated benign pulmonary nodules were summarized. Results: The main etiologies of benign pulmonary nodules were granulomas, hamartomas, cryptococcus infection, organizing pneumonia and non-specific inflammation. In our cohort, we found that the radiological characteristics of benign nodules were single, solid, less than 10 mm in average diameter, with well-defined margins, absence of vacuole sign or vascular convergence , and negative functional imaging. Conclusion: The most common etiologies of post-surgical benign nodules were granulomas, hamartomas, and cryptococcus infection, characterized by being single, solid and with well-defined margins. Caution should be taken before considering surgery for such nodules.

UI	MeSH Term	Description	Entries
D008175	Lung Neoplasms	Tumors or cancer of the LUNG.	Cancer of Lung,Lung Cancer,Pulmonary Cancer,Pulmonary Neoplasms,Cancer of the Lung,Neoplasms, Lung,Neoplasms, Pulmonary,Cancer, Lung,Cancer, Pulmonary,Cancers, Lung,Cancers, Pulmonary,Lung Cancers,Lung Neoplasm,Neoplasm, Lung,Neoplasm, Pulmonary,Pulmonary Cancers,Pulmonary Neoplasm
D003074	Solitary Pulmonary Nodule	A single lung lesion that is characterized by a small round mass of tissue, usually less than 1 cm in diameter, and can be detected by chest radiography. A solitary pulmonary nodule can be associated with neoplasm, tuberculosis, cyst, or other anomalies in the lung, the CHEST WALL, or the PLEURA.	Coin Lesion, Pulmonary,Pulmonary Coin Lesion,Pulmonary Nodule, Solitary,Solitary Lung Nodule,Coin Lesions, Pulmonary,Nodule, Solitary Pulmonary,Nodules, Solitary Pulmonary,Pulmonary Coin Lesions,Pulmonary Nodules, Solitary,Solitary Pulmonary Nodules,Lesion, Pulmonary Coin,Lung Nodule, Solitary,Nodule, Solitary Lung,Solitary Lung Nodules
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective
D014057	Tomography, X-Ray Computed	Tomography using x-ray transmission and a computer algorithm to reconstruct the image.	CAT Scan, X-Ray,CT Scan, X-Ray,Cine-CT,Computerized Tomography, X-Ray,Electron Beam Computed Tomography,Tomodensitometry,Tomography, Transmission Computed,X-Ray Tomography, Computed,CAT Scan, X Ray,CT X Ray,Computed Tomography, X-Ray,Computed X Ray Tomography,Computerized Tomography, X Ray,Electron Beam Tomography,Tomography, X Ray Computed,Tomography, X-Ray Computer Assisted,Tomography, X-Ray Computerized,Tomography, X-Ray Computerized Axial,Tomography, Xray Computed,X Ray Computerized Tomography,X Ray Tomography, Computed,X-Ray Computer Assisted Tomography,X-Ray Computerized Axial Tomography,Beam Tomography, Electron,CAT Scans, X-Ray,CT Scan, X Ray,CT Scans, X-Ray,CT X Rays,Cine CT,Computed Tomography, Transmission,Computed Tomography, X Ray,Computed Tomography, Xray,Computed X-Ray Tomography,Scan, X-Ray CAT,Scan, X-Ray CT,Scans, X-Ray CAT,Scans, X-Ray CT,Tomographies, Computed X-Ray,Tomography, Computed X-Ray,Tomography, Electron Beam,Tomography, X Ray Computer Assisted,Tomography, X Ray Computerized,Tomography, X Ray Computerized Axial,Transmission Computed Tomography,X Ray Computer Assisted Tomography,X Ray Computerized Axial Tomography,X Ray, CT,X Rays, CT,X-Ray CAT Scan,X-Ray CAT Scans,X-Ray CT Scan,X-Ray CT Scans,X-Ray Computed Tomography,X-Ray Computerized Tomography,Xray Computed Tomography
D055613	Multiple Pulmonary Nodules	A number of small lung lesions characterized by small round masses of 2- to 3-mm in diameter. They are usually detected by chest CT scans (COMPUTED TOMOGRAPHY, X-RAY). Such nodules can be associated with metastases of malignancies inside or outside the lung, benign granulomas, or other lesions.	Multiple Pulmonary Nodule,Pulmonary Nodule, Multiple,Pulmonary Nodules, Multiple