-transparent.png){kind=logo}
Postischemic administration of ATP-MgCl2 is known to enhance recovery of renal function and accelerate the restitution of cellular ATP levels. To differentiate between a direct and indirect effect of the exogenous nucleotide, rats were subjected to 45 min of bilateral renal ischemia and were infused with either ATP-MgCl2, AMP-MgCl2, or normal saline. The immediate recovery of the cellular ATP was similar in all three groups of animals, whereas the subsequent recovery was accelerated by the infusion of either nucleotide. Since ATP-MgCl2 and AMP-MgCl2 produced similar results, this study provides evidence that exogenous ATP may act by providing precursors for the resynthesis of the cellular adenine nucleotide pool rather than being a direct source of energy.
M E Stromski, and
K Cooper, and
G Thulin, and
M J Avison, and
K M Gaudio, and
R G Shulman, and
N J Siegel
January 1994,
Life sciences,
M E Stromski, and
K Cooper, and
G Thulin, and
M J Avison, and
K M Gaudio, and
R G Shulman, and
N J Siegel
January 1983,
Clinical and experimental dialysis and apheresis,
M E Stromski, and
K Cooper, and
G Thulin, and
M J Avison, and
K M Gaudio, and
R G Shulman, and
N J Siegel
October 1983,
The American journal of physiology,
M E Stromski, and
K Cooper, and
G Thulin, and
M J Avison, and
K M Gaudio, and
R G Shulman, and
N J Siegel
January 1984,
The American journal of emergency medicine,
M E Stromski, and
K Cooper, and
G Thulin, and
M J Avison, and
K M Gaudio, and
R G Shulman, and
N J Siegel
January 1993,
Life sciences,
M E Stromski, and
K Cooper, and
G Thulin, and
M J Avison, and
K M Gaudio, and
R G Shulman, and
N J Siegel
July 1982,
Kidney international,
M E Stromski, and
K Cooper, and
G Thulin, and
M J Avison, and
K M Gaudio, and
R G Shulman, and
N J Siegel
February 1994,
Journal of applied physiology (Bethesda, Md. : 1985),
M E Stromski, and
K Cooper, and
G Thulin, and
M J Avison, and
K M Gaudio, and
R G Shulman, and
N J Siegel
November 1986,
Biochimica et biophysica acta,
M E Stromski, and
K Cooper, and
G Thulin, and
M J Avison, and
K M Gaudio, and
R G Shulman, and
N J Siegel
February 1989,
The American journal of physiology,
M E Stromski, and
K Cooper, and
G Thulin, and
M J Avison, and
K M Gaudio, and
R G Shulman, and
N J Siegel
January 1960,
Acta - Unio Internationalis Contra Cancrum,
