Arthritis and antinuclear antibodies (ANA) with inherited deficiency of the sixth component of complement (C6). 1986

E Reinitz, and M Lawrence, and B Diamond, and H Keiser, and C Alper

We report here the case of a woman with joint pains found to have antinuclear antibodies and undetectable serum haemolytic complement. Investigation of her and her family members showed an inherited deficiency of C6.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010375 Pedigree The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition. Family Tree,Genealogical Tree,Genealogic Tree,Genetic Identity,Identity, Genetic,Family Trees,Genealogic Trees,Genealogical Trees,Genetic Identities,Identities, Genetic,Tree, Family,Tree, Genealogic,Tree, Genealogical,Trees, Family,Trees, Genealogic,Trees, Genealogical
D003183 Complement C6 A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32 disulfide bonds. C6 is the next complement component to bind to the membrane-bound COMPLEMENT C5B in the assembly of MEMBRANE ATTACK COMPLEX. It is encoded by gene C6. C6 Complement,Complement 6,Complement Component 6,C6, Complement,Complement, C6,Component 6, Complement
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000974 Antibodies, Antinuclear Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease. Anti-DNA Antibodies,Antibodies, Anti-DNA,Antinuclear Antibodies,Antinuclear Autoantibodies,Antinuclear Autoantibody,Antinuclear Factors,Antinuclear Antibody,Antinuclear Factor,Anti DNA Antibodies,Antibody, Antinuclear,Autoantibody, Antinuclear,Factor, Antinuclear
D001168 Arthritis Acute or chronic inflammation of JOINTS. Oligoarthritis,Polyarthritis,Arthritides,Oligoarthritides,Polyarthritides

Related Publications

E Reinitz, and M Lawrence, and B Diamond, and H Keiser, and C Alper
October 1966, The Journal of experimental medicine,
E Reinitz, and M Lawrence, and B Diamond, and H Keiser, and C Alper
February 1978, Journal of immunology (Baltimore, Md. : 1950),
E Reinitz, and M Lawrence, and B Diamond, and H Keiser, and C Alper
January 1998, Immunological investigations,
E Reinitz, and M Lawrence, and B Diamond, and H Keiser, and C Alper
July 1984, Journal of immunology (Baltimore, Md. : 1950),
E Reinitz, and M Lawrence, and B Diamond, and H Keiser, and C Alper
January 1982, Biochemistry,
E Reinitz, and M Lawrence, and B Diamond, and H Keiser, and C Alper
January 1979, Human genetics,
E Reinitz, and M Lawrence, and B Diamond, and H Keiser, and C Alper
April 1976, Thrombosis and haemostasis,
E Reinitz, and M Lawrence, and B Diamond, and H Keiser, and C Alper
March 1996, Journal of immunology (Baltimore, Md. : 1950),
E Reinitz, and M Lawrence, and B Diamond, and H Keiser, and C Alper
February 1983, Biochemical genetics,
E Reinitz, and M Lawrence, and B Diamond, and H Keiser, and C Alper
April 1995, Animal genetics,
Copied contents to your clipboard!