-transparent.png){kind=logo}
Monocyte-derived interleukin 1 (IL 1) induced the platelet activating factor (PAF) production in cultured human endothelial cells (HEC). The product was identified as PAF by the chemical properties, the susceptibility to phospholipase A2 and C and to lipase A1, its behaviour in thin layer chromatography and in high pressure liquid chromatography and the recovery of biological activity tested on rabbit platelets. The action of IL 1 was concentration-dependent and took more than 2 hours to became apparent. Most of the PAF produced was cell-associated and only the 25% of the total was released.
Related Publications
F Bussolino, and
F Breviario, and
C Tetta, and
M Aglietta, and
F Sanavio, and
A Mantovani, and
E Dejana
August 1989,
The American journal of physiology,
F Bussolino, and
F Breviario, and
C Tetta, and
M Aglietta, and
F Sanavio, and
A Mantovani, and
E Dejana
January 1995,
Lung,
F Bussolino, and
F Breviario, and
C Tetta, and
M Aglietta, and
F Sanavio, and
A Mantovani, and
E Dejana
April 1996,
Journal of leukocyte biology,
F Bussolino, and
F Breviario, and
C Tetta, and
M Aglietta, and
F Sanavio, and
A Mantovani, and
E Dejana
March 1986,
Hypertension (Dallas, Tex. : 1979),
F Bussolino, and
F Breviario, and
C Tetta, and
M Aglietta, and
F Sanavio, and
A Mantovani, and
E Dejana
January 1991,
Experimental lung research,
F Bussolino, and
F Breviario, and
C Tetta, and
M Aglietta, and
F Sanavio, and
A Mantovani, and
E Dejana
June 1999,
Molecular human reproduction,
F Bussolino, and
F Breviario, and
C Tetta, and
M Aglietta, and
F Sanavio, and
A Mantovani, and
E Dejana
April 1997,
Inflammation,
F Bussolino, and
F Breviario, and
C Tetta, and
M Aglietta, and
F Sanavio, and
A Mantovani, and
E Dejana
December 1992,
Journal of immunology (Baltimore, Md. : 1950),
F Bussolino, and
F Breviario, and
C Tetta, and
M Aglietta, and
F Sanavio, and
A Mantovani, and
E Dejana
October 1987,
Seminars in thrombosis and hemostasis,
F Bussolino, and
F Breviario, and
C Tetta, and
M Aglietta, and
F Sanavio, and
A Mantovani, and
E Dejana
April 1988,
Thrombosis and haemostasis,
