-transparent.png){kind=logo}
We fractionated, by gel chromatography, sera with high IgE content from atopic subjects and five cases with the hyper-IgE syndrome, and measured the presence of IgE in high molecular weight (HMW) fractions. Two out of four asthmatics and four out of five hyper-IgE had HMW IgE. The same serum fractions gave positive results for conglutinin binding IgG (all six) and IgA (three cases) as well as C1q binding complexes (five cases). IgG auto-antibodies to IgE were also detected together with IgE in HMW fractions. Anti-F(ab)'2 activity was present in five cases (one of them negative for IgG anti-IgE). Our data indicate that complexes made of IgE and IgG anti-IgE are present mainly in patients with chronic allergic symptoms and most frequent in cases of hyper-IgE syndrome.
R Paganelli, and
I Quinti, and
M Carbonari, and
O Pontesilli, and
G P D'Offizi, and
T Letta, and
F Aiuti
April 1988,
The Journal of allergy and clinical immunology,
R Paganelli, and
I Quinti, and
M Carbonari, and
O Pontesilli, and
G P D'Offizi, and
T Letta, and
F Aiuti
January 1993,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
R Paganelli, and
I Quinti, and
M Carbonari, and
O Pontesilli, and
G P D'Offizi, and
T Letta, and
F Aiuti
December 2012,
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology,
R Paganelli, and
I Quinti, and
M Carbonari, and
O Pontesilli, and
G P D'Offizi, and
T Letta, and
F Aiuti
January 1987,
Parasitology research,
R Paganelli, and
I Quinti, and
M Carbonari, and
O Pontesilli, and
G P D'Offizi, and
T Letta, and
F Aiuti
March 1980,
The American journal of tropical medicine and hygiene,
R Paganelli, and
I Quinti, and
M Carbonari, and
O Pontesilli, and
G P D'Offizi, and
T Letta, and
F Aiuti
June 1978,
Revue du rhumatisme et des maladies osteo-articulaires,
R Paganelli, and
I Quinti, and
M Carbonari, and
O Pontesilli, and
G P D'Offizi, and
T Letta, and
F Aiuti
January 2018,
Clinical and molecular allergy : CMA,
R Paganelli, and
I Quinti, and
M Carbonari, and
O Pontesilli, and
G P D'Offizi, and
T Letta, and
F Aiuti
January 1983,
Birth defects original article series,
R Paganelli, and
I Quinti, and
M Carbonari, and
O Pontesilli, and
G P D'Offizi, and
T Letta, and
F Aiuti
February 1984,
The Journal of allergy and clinical immunology,
R Paganelli, and
I Quinti, and
M Carbonari, and
O Pontesilli, and
G P D'Offizi, and
T Letta, and
F Aiuti
June 2015,
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology,
