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In a comparative study 12,080 sera from unpaid donors were tested simultaneously for Hepatitis B Antigen (HBsAg) by enzyme-immunoassay (EIA) and radioimmunoassay (RIA). A relatively high number of sera reacted positive in the EIA-secreening test but were negative after repeated investigation. This percentage could be markedly reduced when using an automated washing apparatus. After neutralization 0.31 per cent were considered as true positive in EIA and RIA, thus demonstrating that no differences did exist as far as sensitivity is concerned. The EIA needs more incubation time than the RIA, however, the EIA has the advantage of using enzyme-labelled antibodies instead of radio-iodinated reagents. The results are read immediately and no sophisticated equipment is required. The EIA is easy to handle, two technicians can perform 1000 tests per day.
S Seidl, and
J Kühner, and
L Trautmann, and
K Pade
January 1978,
Sangre,
S Seidl, and
J Kühner, and
L Trautmann, and
K Pade
August 1980,
Zentralblatt fur Bakteriologie. 1. Abt. Originale. A: Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie,
S Seidl, and
J Kühner, and
L Trautmann, and
K Pade
June 1974,
Klinische Wochenschrift,
S Seidl, and
J Kühner, and
L Trautmann, and
K Pade
September 1974,
Schweizerische medizinische Wochenschrift,
S Seidl, and
J Kühner, and
L Trautmann, and
K Pade
September 1977,
Bollettino dell'Istituto sieroterapico milanese,
S Seidl, and
J Kühner, and
L Trautmann, and
K Pade
December 1979,
Zhonghua Minguo wei sheng wu xue za zhi = Chinese journal of microbiology,
S Seidl, and
J Kühner, and
L Trautmann, and
K Pade
March 1977,
Bratislavske lekarske listy,
S Seidl, and
J Kühner, and
L Trautmann, and
K Pade
June 1974,
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie,
S Seidl, and
J Kühner, and
L Trautmann, and
K Pade
September 2004,
Journal of family & community medicine,
S Seidl, and
J Kühner, and
L Trautmann, and
K Pade
March 1981,
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases,
