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Semi-quantitative scores can be used as an adjunct to visual assessment in rubidium-82 positron emission tomography (82Rb PET). The semi-quantitative cut-off values used in 82Rb PET are derived from single-photon emission computed tomography (SPECT). It is unknown whether these cut-off values can be extrapolated to 82Rb PET. We compared the semi-quantitative with the visual assessment of ischemia and determined which summed difference score (SDS) score predicts ischemia best. We included 108 patients who underwent 82Rb PET imaging and performed visual and semi-quantitative assessment. A scan with a SDS ≥ 2 and a summed stress score (SSS) ≥ 4 was considered to demonstrate ischemia. We compared the semi-quantitative with the visual assessment. 41 (38%) Normal scans, and 67 (62%) scans with ischemia and/or an irreversible defect were included. The semi-quantitative assessment showed ischemia more often than the visual assessment (51% vs 29%, P < .001). Patients with a low or intermediate pre-test probability of coronary artery disease (CAD) and a SDS < 4 did not demonstrate ischemia by visual assessment. Semi-quantitative assessment in 82Rb PET imaging clearly demonstrates the presence of ischemia. Ischemia is unlikely in patients with low and intermediate pre-test probability of CAD and a SDS < 4.
N M Borren, and
T J Gerritse, and
J P Ottervanger, and
M Mouden, and
J R Timmer, and
J A van Dalen, and
P L Jager, and
J D van Dijk
December 2013,
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
N M Borren, and
T J Gerritse, and
J P Ottervanger, and
M Mouden, and
J R Timmer, and
J A van Dalen, and
P L Jager, and
J D van Dijk
May 2014,
Clinical physiology and functional imaging,
N M Borren, and
T J Gerritse, and
J P Ottervanger, and
M Mouden, and
J R Timmer, and
J A van Dalen, and
P L Jager, and
J D van Dijk
January 2015,
Frontiers in medicine,
N M Borren, and
T J Gerritse, and
J P Ottervanger, and
M Mouden, and
J R Timmer, and
J A van Dalen, and
P L Jager, and
J D van Dijk
February 2022,
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
N M Borren, and
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J P Ottervanger, and
M Mouden, and
J R Timmer, and
J A van Dalen, and
P L Jager, and
J D van Dijk
August 2017,
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N M Borren, and
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J D van Dijk
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N M Borren, and
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J D van Dijk
August 1996,
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N M Borren, and
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J D van Dijk
June 2019,
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
N M Borren, and
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M Mouden, and
J R Timmer, and
J A van Dalen, and
P L Jager, and
J D van Dijk
January 2015,
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N M Borren, and
T J Gerritse, and
J P Ottervanger, and
M Mouden, and
J R Timmer, and
J A van Dalen, and
P L Jager, and
J D van Dijk
December 2023,
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
