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Synthesis of Ester-Substituted Indolo[2,1-a]isoquinolines via Photocatalyzed Alkoxycarbonylation/Cyclization Reactions. 2022

Jian-Qiang Chen, and Xiaodong Tu, and Binyan Qin, and Shaoxin Huang, and Jun Zhang, and Jie Wu
School of Pharmaceutical and Materials Engineering and Institute for Advanced Studies, Taizhou University, Taizhou 318000, China.

A direct alkoxycarbonylation/cyclization reaction is accomplished under visible light-induced photoredox catalysis. With this approach, a variety of ester-substituted indolo[2,1-a]isoquinolines are prepared in good to excellent yields. It is worth noting that this method not only can afford the synthesis of indolo[2,1-a]isoquinolines but also can provide an alternative route for generating complex target structures bearing carboxylic esters.

UI MeSH Term Description Entries

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