[Value of propofol in microsurgery of the middle ear]. 1987

D Lecomte, and C Vulser, and P Dassier, and M T Cousin
Département d'Anesthésie-Réanimation Chirurgicale, Hôpital Broussais, Paris.

In 21 anaesthetics on patients ASA I-II undergoing middle ear microsurgery, the induction was done by 2 mg/kg propofol and 2 mcg/kg fentanyl. Anaesthesia was maintained by a continuous infusion of propofol 100 mcg/kg/min and bolus injections of fentanyl 1 mcg/kg every 30 min, and controlled ventilation with 60% Nitrous Oxide. The side effects during induction and recovery were minor. After a slight fall in blood pressure at induction, the haemodynamic values were steady during the whole surgery. Haemostasis was always good: the operating field was bloodless in 13 patients (62%), relatively bloody in 8 (38%), but never inconvenient for the surgeon. While recovery happened later than in other studies, the time from eyes opening to complete consciousness was always short, less than 10 minutes. The adjunction of fentanyl could be responsible for the long recovery time. No correlation is found between the infusion rate of propofol and recovery time. All patients but one are satisfied with their anaesthesia, especially with their smooth recovery.

UI MeSH Term Description Entries
D008297 Male Males
D008866 Microsurgery The performance of surgical procedures with the aid of a microscope.
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009609 Nitrous Oxide Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream. Laughing Gas,Nitrogen Protoxide,Gas, Laughing,Oxide, Nitrous
D010636 Phenols Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.
D003258 Consumer Behavior Behavior associated with the procurement of goods, services, or experiences. Consumer Preference,Consumer Satisfaction,Behavior, Consumer,Behaviors, Consumer,Consumer Behaviors,Consumer Preferences,Preference, Consumer,Preferences, Consumer,Satisfaction, Consumer
D004432 Ear, Middle The space and structures directly internal to the TYMPANIC MEMBRANE and external to the inner ear (LABYRINTH). Its major components include the AUDITORY OSSICLES and the EUSTACHIAN TUBE that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat. Tympanic Cavity,Tympanum,Middle Ear,Cavities, Tympanic,Cavity, Tympanic,Ears, Middle,Middle Ears,Tympanic Cavities,Tympanums
D005260 Female Females
D005283 Fentanyl A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078) Phentanyl,Duragesic,Durogesic,Fentanest,Fentanyl Citrate,Fentora,R-4263,Sublimaze,Transmucosal Oral Fentanyl Citrate,R 4263,R4263
D006439 Hemodynamics The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM. Hemodynamic

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