A 74-year-old woman underwent right hemicolectomy for ascending colon cancer in March 2013, after which she received adjuvant chemotherapy(UFT plus UZEL)for 6 months. In October 2014, left supraclavicular lymphadenopathy appeared, and it was diagnosed as adenocarcinoma metastasis through fine-needle aspiration cytology. CT revealed swelling of left supraclavicular lymph nodes and para-aortic lymph nodes but no metastases to other organs. Exclusion diagnosis was performed, and they were diagnosed as multiple distant lymph node metastases. Chemotherapy(mFOLFOX6 plus bevacizumab) was started in December 2014, and all swollen lymph nodes shrank and disappeared on CT in July 2015. Furthermore, there was no swelling of lymph nodes or appearance of new lesions on CT in December 2015, as the response to treatment was judged to be complete. In addition, the regimen was changed to FOLFIRI plus bevacizumab because side effects such as peripheral neuropathy were worsening. Although chemotherapy was discontinued in November 2016, there has been no recurrence and a long-term complete response has been sustained.