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Most challenges during the development of solid dosage forms are related to the impact of any variations in raw material properties, batch size, or equipment scales on the product quality and the control of the manufacturing process. With the ever pertinent restrictions on time and resource availability versus heightened expectations to develop, optimize, and troubleshoot manufacturing processes, targeted and robust science-based process modeling platforms are essential. This review focuses on the modeling of unit operations and practices involved in batch manufacturing of solid dosage forms by direct compaction. An effort is made to highlight the key advances in the past five years, and to propose potentially beneficial future study directions.
Alexander Russell, and
John Strong, and
Sean Garner, and
William Ketterhagen, and
Michelle Long, and
Maxx Capece
April 2015,
International journal of pharmaceutics,
Alexander Russell, and
John Strong, and
Sean Garner, and
William Ketterhagen, and
Michelle Long, and
Maxx Capece
December 2012,
Journal of pharmaceutical sciences,
Alexander Russell, and
John Strong, and
Sean Garner, and
William Ketterhagen, and
Michelle Long, and
Maxx Capece
March 2022,
Pharmaceutics,
Alexander Russell, and
John Strong, and
Sean Garner, and
William Ketterhagen, and
Michelle Long, and
Maxx Capece
January 2022,
Mathematical biosciences and engineering : MBE,
Alexander Russell, and
John Strong, and
Sean Garner, and
William Ketterhagen, and
Michelle Long, and
Maxx Capece
November 1999,
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V,
Alexander Russell, and
John Strong, and
Sean Garner, and
William Ketterhagen, and
Michelle Long, and
Maxx Capece
August 2019,
International journal of pharmaceutics,
Alexander Russell, and
John Strong, and
Sean Garner, and
William Ketterhagen, and
Michelle Long, and
Maxx Capece
June 2018,
Materials (Basel, Switzerland),
Alexander Russell, and
John Strong, and
Sean Garner, and
William Ketterhagen, and
Michelle Long, and
Maxx Capece
November 2019,
Computer methods in biomechanics and biomedical engineering,
Alexander Russell, and
John Strong, and
Sean Garner, and
William Ketterhagen, and
Michelle Long, and
Maxx Capece
February 2006,
Pharmaceutical development and technology,
Alexander Russell, and
John Strong, and
Sean Garner, and
William Ketterhagen, and
Michelle Long, and
Maxx Capece
February 2022,
Journal of pharmaceutical sciences,
