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Sustained Eosinophilic Cholangitis Due to a Mite Allergy Mimicking Sclerosing Cholangitis. 2022
Masayo Motoya, and
Shun Takai, and
Hiroshi Moriya, and
Takehiro Hirano, and
Kohei Wagatsuma, and
Yasunao Numata, and
Yujiro Kawakami, and
Yoshiharu Masaki, and
Keisuke Ishigami, and
Ayako Murota, and
Hiroshi Nakase
Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Japan.
Eosinophilic cholangiopathy (EC) presents with thickening and stenosis of the bile duct wall that is histologically characterized by eosinophil infiltration. The diagnosis is often difficult. We herein report a patient who had been followed up with a diagnosis of primary sclerosing cholangitis but had a final diagnosis of EC based on eosinophilia, histological findings of bile duct and liver biopsy specimens, and a review of a previous surgical specimen of the gallbladder. Antigen tests, isolation from her house, and accidental re-exposure to the antigen revealed that the causative antigen was the mite Dermatophagoides pteronyssinus.
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