OBJECTIVE The purpose of this study was to assess the prevalence of malocclusion in primary dentition of children in southeast part of Haryana state in India. METHODS About 1,540 children of age 3-5 years from 10 nursery and 10 primary schools were selected across Rohtak city. The children were selected by stratified random technique and examined at their respective schools. Oral examination was done to record the parameters such as molar relation, canine relation, crowding, spacing, midline shift, overjet, overbite, rotations, supernumerary teeth, tooth wear, anterior crossbite, and open bite. Chi-square test was used for calculating p-value. RESULTS Class I canine relations was seen in 66.2%, flush terminal plane, mesial step, and distal step were observed in 60%, 30.8%, 9.2%, respectively. Midline shift was observed in 1.8% in maxilla and 4% cases in mandible. Rotations were more prevalent in mandibular dentition (26%). Supernumerary teeth were found to be 0.4% in maxillary arch. Spacing was reported in 81.9% in maxillary dentition and 69% in mandibular dentition. Increased overjet and overbite was present in 10.3% and 30.9%, respectively. Anterior crossbite and anterior open bite were seen in only 1% and 1.9% children, respectively with statistically significant higher prevalence in males. Prevalence of attritional facets were reported 13% in enamel and 8% in dentin. CONCLUSIONS There is a high prevalence of class I canine relation, flush terminal plane molar, and spaced dentitions, suggestive of low prevalence of malocclusion in primary dentition in Rohtak district of Haryana state. The results may provide a baseline data for further research on a larger scale. Sharma K, Bihani T, Kumar V. Prevalence of Malocclusion in Primary Dentition in Southeast Part of Haryana, India: A Cross-sectional Study. Int J Clin Pediatr Dent 2021;14(6):757-761.