-transparent.png){kind=logo}
Using four different digoxin kits, it was disclosed that the majority of various samples including amniotic fluid, cord blood, and serum from neonates contained substantial levels of digoxin-like immunoreactive substance. The differences in data seemed to be due to the range of epitopes which are recognized by antidigoxin antiserum. The day-to-day studies on sera serially obtained from infants at birth to 48 days old revealed that the level of the substance (0.31 +/- 0.12 ng/ml) in sera of the 1-day-old neonates rapidly declined to the level of 0.1 ng/ml by the 2nd postnatal wk and thereafter gradually declined. The immunological specificity and accuracy of the detection of digoxin-like immunoreactive substance was confirmed by a sample dilution test, a recovery test for standard digoxin, and an absorption test with antidigoxin antiserum. The amniotic fluid and cord blood also contained four to eight times more of a digitoxin-like immunoreactive substance than they did digoxin-like immunoreactive substance. A significant correlation was observed between the levels of digoxin-like immunoreactive substance and of digitoxin-like immunoreactive substance (p less than 0.01).
H Ebara, and
S Suzuki, and
K Nagashima, and
T Koizumi, and
A Nishida, and
Y Kanbe, and
T Kuroume
April 2001,
American journal of clinical pathology,
H Ebara, and
S Suzuki, and
K Nagashima, and
T Koizumi, and
A Nishida, and
Y Kanbe, and
T Kuroume
August 1986,
Clinical biochemistry,
H Ebara, and
S Suzuki, and
K Nagashima, and
T Koizumi, and
A Nishida, and
Y Kanbe, and
T Kuroume
January 1986,
Clinical chemistry,
H Ebara, and
S Suzuki, and
K Nagashima, and
T Koizumi, and
A Nishida, and
Y Kanbe, and
T Kuroume
April 1995,
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine,
H Ebara, and
S Suzuki, and
K Nagashima, and
T Koizumi, and
A Nishida, and
Y Kanbe, and
T Kuroume
March 1987,
European journal of pediatrics,
H Ebara, and
S Suzuki, and
K Nagashima, and
T Koizumi, and
A Nishida, and
Y Kanbe, and
T Kuroume
July 2000,
European heart journal,
H Ebara, and
S Suzuki, and
K Nagashima, and
T Koizumi, and
A Nishida, and
Y Kanbe, and
T Kuroume
July 1985,
Clinical chemistry,
H Ebara, and
S Suzuki, and
K Nagashima, and
T Koizumi, and
A Nishida, and
Y Kanbe, and
T Kuroume
March 1993,
Zhonghua nei ke za zhi,
H Ebara, and
S Suzuki, and
K Nagashima, and
T Koizumi, and
A Nishida, and
Y Kanbe, and
T Kuroume
March 1990,
Therapeutic drug monitoring,
H Ebara, and
S Suzuki, and
K Nagashima, and
T Koizumi, and
A Nishida, and
Y Kanbe, and
T Kuroume
April 1987,
Lancet (London, England),
