This study investigated the effects of meditation/relaxation on physiological responses during the performance of a fine motor and a gross motor task. A pretest-posttest control group, randomized-blocks design was used to study a group of 16 meditators and a group of 16 nonmeditators, subgroups of each who relaxed prior to performing on a pursuit-rotor tracking device as a fine motor task and to performing the Luft cycle ergometer protocol to a heart rate of 70% of age-adjusted maximum heart rate as a gross motor task. During each of these tasks heart rate, systolic blood pressure, rate-pressure-product, and EMG activity of the frontalis muscle were monitored. No significant difference in the performance of either the fine motor or the gross motor task was noted for persons practicing meditation and persons who were nonmeditators but were given the opportunity to relax prior to a motor task. Likewise, no significant difference was noted in the pattern of response to the imposed fine motor or gross motor task by meditators or relaxed nonmeditators.