Childhood trauma exposure and personality traits in schizophrenia patients. 2022

Christopher Adanty, and Jessica Qian, and Yin Wang, and Gary Remington, and Ahmad Shakeri, and Carol Borlido, and Philip Gerretsen, and Ariel Graff-Guerrero, and Vincenzo De Luca
Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

Childhood trauma in schizophrenia (SCZ) is associated with aberrant neurobiological downstream effects and cognitive deficits that markedly hinder patient outcome and functioning. However, the relationship between specific forms of childhood abuse and the tendency for certain personality traits in patients with SCZ has not been comprehensively studied yet. We recruited 374 SCZ patients and screened for history of physical abuse (PA), emotional abuse (EA), sexual abuse (SA), physical neglect (PN) and emotional neglect (EN) using the Childhood Trauma Questionnaire and measured personality traits using the NEO Five-Factor inventory. Using CTQ cut-off scores, the prevalence of EA, PA, SA, EN and PN was 60.7%, 42.0%, 37.7%, 64.2% and 54.3% respectively. Exposure to any form of childhood abuse was associated with increased neuroticism. Exposure to EA, SA, PN and EN was correlated with decreased agreeableness and conscientiousness scores. PN, EN and PA exposure was associated with decreased openness while EA, PN and EN exposure was associated with decreased extraversion. Furthermore, a positive correlation was found between all forms of childhood abuse and trait neuroticism whereas negative correlations were found between certain forms of childhood abuse and all other personality traits. Exposure to specific forms of childhood abuse was associated with specific personality traits in patients with SCZ.

UI MeSH Term Description Entries
D010551 Personality Behavior-response patterns that characterize the individual. Personalities
D010555 Personality Inventory Check list, usually to be filled out by a person about himself, consisting of many statements about personal characteristics which the subject checks. Edwards Personal Preference Schedule,Myers-Briggs Type Indicator,Indicator, Myers-Briggs Type,Inventories, Personality,Inventory, Personality,Myers Briggs Type Indicator,Personality Inventories
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002649 Child Abuse Abuse of children in a family, institutional, or other setting. (APA, Thesaurus of Psychological Index Terms, 1994) Abuse Experiences, Childhood,Child Neglect,Child Neglect Experiences,Child Neglect, Physical,Childhood Abuse Experiences,Childhood Neglect Experiences,Neglect Experience, Childhood,Neglect Experiences, Childhood,Physical Neglect, Childhood,Child Maltreatment,Child Mistreatment,Abuse Experience, Childhood,Abuse, Child,Child Neglect Experience,Childhood Abuse Experience,Childhood Neglect Experience,Childhood Physical Neglect,Childhood Physical Neglects,Experience, Child Neglect,Experience, Childhood Abuse,Experience, Childhood Neglect,Maltreatment, Child,Mistreatment, Child,Neglect Experience, Child,Neglect, Child,Neglect, Childhood Physical,Neglect, Physical Child,Physical Child Neglect,Physical Child Neglects
D005120 Extraversion, Psychological A state in which attention is largely directed outward from the self. Extraversion (Psychology),Extraversion, Psychology,Extroversion, Psychological,Extroversion, Psychology,Extraversion,Extroversion,Extroversion (Psychology),Psychological Extraversion,Psychological Extroversion,Psychology Extraversion,Psychology Extraversions,Psychology Extroversion
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000075384 Neuroticism Personality trait related to tendency to respond to threat, frustration or a loss with negative emotions (e.g., ANGER; ANXIETY; FRUSTRATION; embarrassment and sadness). Neuroticism Traits,Neuroticism Trait
D000076783 Adverse Childhood Experiences Deleterious experiences in first 18 years of life. Adolescent Trauma,Childhood Trauma,Early Life Stress,Early-Life Stress,Traumatic Childhood Experiences,Adolescent Traumas,Adverse Childhood Experience,Childhood Experience, Adverse,Childhood Experience, Traumatic,Childhood Experiences, Adverse,Childhood Experiences, Traumatic,Childhood Traumas,Early Life Stresses,Early-Life Stresses,Experience, Traumatic Childhood,Experiences, Traumatic Childhood,Life Stress, Early,Life Stresses, Early,Stress, Early Life,Stress, Early-Life,Stresses, Early Life,Stresses, Early-Life,Trauma, Adolescent,Trauma, Childhood,Traumas, Adolescent,Traumas, Childhood,Traumatic Childhood Experience
D012559 Schizophrenia A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior. Dementia Praecox,Schizophrenic Disorders,Disorder, Schizophrenic,Disorders, Schizophrenic,Schizophrenias,Schizophrenic Disorder

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