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Resistance to pulmonary aspergillosis was studied in groups of rabbits exposed to aerosolized spores of Aspergillus fumigatus for 15 minutes on successive days for a total of 10, 7, or 4 exposures or a single exposure. The results of the study demonstrated that exposure of rabbits to spores for 15 minutes on 10 successive days did not result in an accumulation of viable spores in excess of those present in the lungs of rabbits exposed a single time. The tissue response in the lungs of the rabbits exposed at multiple times was more intense than that in the rabbits exposed once, but resolution of the lesions occurred similarly in terms of time and completeness of resolution. The duration of the antibody response as determined by a passive hemagglutination test and by enzyme-linked immunosorbent assay correlated with the number of exposures to spores, in that rabbits exposed 10 or 7 times to aerosolized spores remained positive longer than did those exposed fewer times. The results of the precipitin tests in agar gel were negative in all the rabbits but one.
J R Thurston, and
W M Peden, and
K M Driftmier, and
J L Richard
July 1975,
American journal of veterinary research,
J R Thurston, and
W M Peden, and
K M Driftmier, and
J L Richard
January 1984,
Immunobiology,
J R Thurston, and
W M Peden, and
K M Driftmier, and
J L Richard
May 2017,
Risk analysis : an official publication of the Society for Risk Analysis,
J R Thurston, and
W M Peden, and
K M Driftmier, and
J L Richard
December 1988,
American journal of veterinary research,
J R Thurston, and
W M Peden, and
K M Driftmier, and
J L Richard
March 1982,
Mycopathologia,
J R Thurston, and
W M Peden, and
K M Driftmier, and
J L Richard
June 2023,
Journal of fungi (Basel, Switzerland),
J R Thurston, and
W M Peden, and
K M Driftmier, and
J L Richard
February 1971,
Mycopathologia et mycologia applicata,
J R Thurston, and
W M Peden, and
K M Driftmier, and
J L Richard
January 1995,
International archives of allergy and immunology,
J R Thurston, and
W M Peden, and
K M Driftmier, and
J L Richard
January 2014,
Journal of immunotoxicology,
J R Thurston, and
W M Peden, and
K M Driftmier, and
J L Richard
July 2009,
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases,
