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Seventy-seven patients with advanced gastric carcinoma were prospectively randomized to receive 5-FU and carmustine (FB) with or without doxorubicin (FAB). Thirty-five patients were evaluable for response. Neither the response rates (partial remission, 11% for FB and 24% for FAB) nor survival times (median, 4.0 months for FB and 5.5 months for FAB) were statistically different. The median survival of patients with partial remission (7.8 months) and those with no change (7.4 months) was significantly prolonged compared to patients with progressive disease (4.5 months). The side effects of both regimens after the first treatment cycle (except alopecia in FAB) were low. After the second cycle more pronounced myelosuppression in the FAB arm was observed.
G Schnitzler, and
W Queisser, and
M E Heim, and
H König, and
R Katz, and
D Fritze, and
R Herrmann, and
H Arnold, and
H Henss, and
F A Trux
October 1984,
Cancer treatment reports,
G Schnitzler, and
W Queisser, and
M E Heim, and
H König, and
R Katz, and
D Fritze, and
R Herrmann, and
H Arnold, and
H Henss, and
F A Trux
October 1991,
Annals of oncology : official journal of the European Society for Medical Oncology,
G Schnitzler, and
W Queisser, and
M E Heim, and
H König, and
R Katz, and
D Fritze, and
R Herrmann, and
H Arnold, and
H Henss, and
F A Trux
January 1990,
Acta oncologica (Stockholm, Sweden),
G Schnitzler, and
W Queisser, and
M E Heim, and
H König, and
R Katz, and
D Fritze, and
R Herrmann, and
H Arnold, and
H Henss, and
F A Trux
June 1993,
Cancer,
G Schnitzler, and
W Queisser, and
M E Heim, and
H König, and
R Katz, and
D Fritze, and
R Herrmann, and
H Arnold, and
H Henss, and
F A Trux
January 1985,
Oncology,
G Schnitzler, and
W Queisser, and
M E Heim, and
H König, and
R Katz, and
D Fritze, and
R Herrmann, and
H Arnold, and
H Henss, and
F A Trux
April 1986,
Cancer treatment reports,
G Schnitzler, and
W Queisser, and
M E Heim, and
H König, and
R Katz, and
D Fritze, and
R Herrmann, and
H Arnold, and
H Henss, and
F A Trux
December 1982,
Cancer treatment reports,
G Schnitzler, and
W Queisser, and
M E Heim, and
H König, and
R Katz, and
D Fritze, and
R Herrmann, and
H Arnold, and
H Henss, and
F A Trux
January 1980,
Cancer treatment reports,
G Schnitzler, and
W Queisser, and
M E Heim, and
H König, and
R Katz, and
D Fritze, and
R Herrmann, and
H Arnold, and
H Henss, and
F A Trux
January 1986,
Oncology,
G Schnitzler, and
W Queisser, and
M E Heim, and
H König, and
R Katz, and
D Fritze, and
R Herrmann, and
H Arnold, and
H Henss, and
F A Trux
January 1981,
Cancer treatment reports,
