Biomaterial Database

Use of colchicine in Behçet's syndrome. 1986

H M Sander, and H W Randle

Colchicine is of benefit in the treatment of ocular, articular, oral, and genital lesions in BS. Polymorphonuclear neutrophil function, which is important in the pathogenesis of the disease, is modified by the drug. There is no evidence that colchicine alters the tendency for this disease to become chronic; however, the drug lessens the severity of certain manifestations and does not have the more deleterious side effects of prolonged steroid and immunosuppressive regimens.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D011239	Prednisolone	A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.	Di-Adreson-F,Predate,Predonine,Di Adreson F,DiAdresonF
D003078	Colchicine	A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE).	Colchicine, (+-)-Isomer,Colchicine, (R)-Isomer
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D001528	Behcet Syndrome	Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.	Behcet Disease,Behcet's Disease,Behcet's Syndrome,Triple-Symptom Complex,Adamantiades-Behcet Disease,Behcet Triple Symptom Complex,Behçet Disease,Old Silk Route Disease,Triple Symptom Complex,Adamantiades Behcet Disease,Adamantiades-Behcet Diseases,Behçet Diseases,Symptom Complex, Triple,Triple Symptom Complices

Related Publications

H M Sander, and H W Randle

Behçet's syndrome treated with colchicine.

April 1991, The Netherlands journal of medicine,

H M Sander, and H W Randle

[Treatment of Behçet's syndrome with colchicine].

June 1989, Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques,

H M Sander, and H W Randle

Behçet's syndrome and treatment with colchicine.

April 1981, Journal of the American Academy of Dermatology,

H M Sander, and H W Randle

Use of colchicine in the treatment of Behçet's disease.

November 1982, International journal of dermatology,

H M Sander, and H W Randle

[Use of colchicine in the treatment of Behçet's disease].

January 1985, Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia,

H M Sander, and H W Randle

A double-blind trial of colchicine in Behçet's syndrome.

November 2001, Arthritis and rheumatism,