In an extensive series of experimental studies conducted on the common carotid artery in rats, a combined technique involving suture and gluing with human fibrin glue has been developed. In view of the good results achieved, this technique was then applied in 12 patients in whom anastomosis between the superficial temporal artery and a cortical branch of the middle cerebral artery was carried out. This modified surgical technique shortened the duration of operation and also reduced the incidence of complications. Late results, too, seem to be more satisfactory, as far as can be ascertained within the given observation period. 10 patients showed a marked improvement in the clinical neurological findings. Working capacity was completely restored in 5 out of these patients. In one patient, clinical symptoms deteriorated on account of an intra-operative contralateral cerebral haemorrhage. The condition of one patient remained unchanged.