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A murine monoclonal antibody (ECS-1) was prepared from BALB/c mice immunized with trypsinized cultured human foreskin keratinocytes. The antibody showed a pattern suggestive of intercellular staining on the nucleated layers of normal human epidermis, adult palm, mouse lip epidermis, and cultured human keratinocytes. ECS-1 stained human fetal skin by 9 weeks estimated gestational age. ECS-1 reacted with a 35 kD protein extracted from neonatal foreskin epidermis and cultured human keratinocytes. The protein required Nonidet P-40 or sodium dodecyl sulfate and mercaptoethanol for solubilization. ECS-1 induced epidermal cell detachment which was enhanced by complement. ECS-1 shares characteristics with human pemphigus antibodies.
M Negi, and
A T Lane, and
P E McCoon, and
J A Fairley, and
L A Goldsmith
November 1991,
British journal of haematology,
M Negi, and
A T Lane, and
P E McCoon, and
J A Fairley, and
L A Goldsmith
October 1990,
Clinical and experimental immunology,
M Negi, and
A T Lane, and
P E McCoon, and
J A Fairley, and
L A Goldsmith
January 1991,
Experimental hematology,
M Negi, and
A T Lane, and
P E McCoon, and
J A Fairley, and
L A Goldsmith
June 2000,
Journal of neurochemistry,
M Negi, and
A T Lane, and
P E McCoon, and
J A Fairley, and
L A Goldsmith
July 2003,
Biotechnology and bioengineering,
M Negi, and
A T Lane, and
P E McCoon, and
J A Fairley, and
L A Goldsmith
November 1987,
Clinical and experimental immunology,
M Negi, and
A T Lane, and
P E McCoon, and
J A Fairley, and
L A Goldsmith
March 1988,
British journal of cancer,
M Negi, and
A T Lane, and
P E McCoon, and
J A Fairley, and
L A Goldsmith
February 1989,
Transplantation proceedings,
M Negi, and
A T Lane, and
P E McCoon, and
J A Fairley, and
L A Goldsmith
January 1983,
Hybridoma,
M Negi, and
A T Lane, and
P E McCoon, and
J A Fairley, and
L A Goldsmith
January 1989,
Archives of dermatological research,
