BIOMAT Database Logo BIOMAT Database Logo

Metronidazole Induced Cerebellar Toxicity: A Case Report. 2021

Shova Sapkota, and Aliska Niroula, and Rina Prajapati, and Subhani Sharma, and Krishna Dhungana
Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.

Metronidazole is a widely used antibiotic against bacterial and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We present a case of a 55-years male presented with dysarthria, who had positive cerebellar sign and magnetic resonance imaging findings suggestive of metronidazole induced cerebellar toxicity following metronidazole therapy for two months in a case of liver abscess. And, the symptoms resolved after cessation of metronidazole.

UI MeSH Term Description Entries
D008279 Magnetic Resonance Imaging Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques. Chemical Shift Imaging,MR Tomography,MRI Scans,MRI, Functional,Magnetic Resonance Image,Magnetic Resonance Imaging, Functional,Magnetization Transfer Contrast Imaging,NMR Imaging,NMR Tomography,Tomography, NMR,Tomography, Proton Spin,fMRI,Functional Magnetic Resonance Imaging,Imaging, Chemical Shift,Proton Spin Tomography,Spin Echo Imaging,Steady-State Free Precession MRI,Tomography, MR,Zeugmatography,Chemical Shift Imagings,Echo Imaging, Spin,Echo Imagings, Spin,Functional MRI,Functional MRIs,Image, Magnetic Resonance,Imaging, Magnetic Resonance,Imaging, NMR,Imaging, Spin Echo,Imagings, Chemical Shift,Imagings, Spin Echo,MRI Scan,MRIs, Functional,Magnetic Resonance Images,Resonance Image, Magnetic,Scan, MRI,Scans, MRI,Shift Imaging, Chemical,Shift Imagings, Chemical,Spin Echo Imagings,Steady State Free Precession MRI
D008297 Male Males
D008795 Metronidazole A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. 2-Methyl-5-nitroimidazole-1-ethanol,Bayer 5360,Clont,Danizol,Flagyl,Gineflavir,Metric,MetroGel,Metrodzhil,Metrogyl,Metronidazole Hydrochloride,Metronidazole Monohydrochloride,Metronidazole Phosphate,Metronidazole Phosphoester,Satric,Trichazol,Trichopol,Trivazol,Vagilen,2 Methyl 5 nitroimidazole 1 ethanol
D001927 Brain Diseases Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. Intracranial Central Nervous System Disorders,Brain Disorders,CNS Disorders, Intracranial,Central Nervous System Disorders, Intracranial,Central Nervous System Intracranial Disorders,Encephalon Diseases,Encephalopathy,Intracranial CNS Disorders,Brain Disease,Brain Disorder,CNS Disorder, Intracranial,Encephalon Disease,Encephalopathies,Intracranial CNS Disorder
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000900 Anti-Bacterial Agents Substances that inhibit the growth or reproduction of BACTERIA. Anti-Bacterial Agent,Anti-Bacterial Compound,Anti-Mycobacterial Agent,Antibacterial Agent,Antibiotics,Antimycobacterial Agent,Bacteriocidal Agent,Bacteriocide,Anti-Bacterial Compounds,Anti-Mycobacterial Agents,Antibacterial Agents,Antibiotic,Antimycobacterial Agents,Bacteriocidal Agents,Bacteriocides,Agent, Anti-Bacterial,Agent, Anti-Mycobacterial,Agent, Antibacterial,Agent, Antimycobacterial,Agent, Bacteriocidal,Agents, Anti-Bacterial,Agents, Anti-Mycobacterial,Agents, Antibacterial,Agents, Antimycobacterial,Agents, Bacteriocidal,Anti Bacterial Agent,Anti Bacterial Agents,Anti Bacterial Compound,Anti Bacterial Compounds,Anti Mycobacterial Agent,Anti Mycobacterial Agents,Compound, Anti-Bacterial,Compounds, Anti-Bacterial
D020258 Neurotoxicity Syndromes Neurologic disorders caused by exposure to toxic substances through ingestion, injection, cutaneous application, or other method. This includes conditions caused by biologic, chemical, and pharmaceutical agents. Poisoning, Nervous System,Encephalopathy, Toxic,Nervous System Poisoning,Neurotoxic Disorders,Neurotoxin Diseases,Neurotoxin Disorders,Toxic Encephalitis,Encephalitides, Toxic,Encephalitis, Toxic,Encephalopathies, Toxic,Nervous System Poisonings,Neurotoxic Disorder,Neurotoxicity Syndrome,Neurotoxin Disease,Neurotoxin Disorder,Poisonings, Nervous System,Syndrome, Neurotoxicity,Syndromes, Neurotoxicity,Toxic Encephalitides,Toxic Encephalopathies,Toxic Encephalopathy

Related Publications

Shova Sapkota, and Aliska Niroula, and Rina Prajapati, and Subhani Sharma, and Krishna Dhungana
Metronidazole-induced cerebellar toxicity.
August 2010, Pediatric radiology,
Shova Sapkota, and Aliska Niroula, and Rina Prajapati, and Subhani Sharma, and Krishna Dhungana
Metronidazole-Induced Cerebellar Toxicity.
April 2016, Neurology international,
Shova Sapkota, and Aliska Niroula, and Rina Prajapati, and Subhani Sharma, and Krishna Dhungana
Metronidazole-induced encephalopathy delayed diagnosis due to cerebellar infarction: A case report.
February 2023, Medicine,
Shova Sapkota, and Aliska Niroula, and Rina Prajapati, and Subhani Sharma, and Krishna Dhungana
Reversible metronidazole-induced cerebellar toxicity in a multiple transplant recipient.
October 2009, Journal of the neurological sciences,
Shova Sapkota, and Aliska Niroula, and Rina Prajapati, and Subhani Sharma, and Krishna Dhungana
Metronidazole induced cerebellar toxicity after prolonged treatment of large multiloculated pyogenic liver abscess; A case report and literature review.
January 2023, IDCases,
Shova Sapkota, and Aliska Niroula, and Rina Prajapati, and Subhani Sharma, and Krishna Dhungana
Metronidazole-Induced Encephalopathy: A Case Report.
January 2016, Journal of Nippon Medical School = Nippon Ika Daigaku zasshi,
Shova Sapkota, and Aliska Niroula, and Rina Prajapati, and Subhani Sharma, and Krishna Dhungana
Metronidazole-induced cerebellar syndrome.
May 2021, Postgraduate medical journal,
Shova Sapkota, and Aliska Niroula, and Rina Prajapati, and Subhani Sharma, and Krishna Dhungana
Metronidazole induced cerebellar ataxia.
January 2013, Indian journal of pharmacology,
Shova Sapkota, and Aliska Niroula, and Rina Prajapati, and Subhani Sharma, and Krishna Dhungana
Metronidazole-Induced Recurrent Paresthesia: A Case Report.
January 2021, Neurology India,
Shova Sapkota, and Aliska Niroula, and Rina Prajapati, and Subhani Sharma, and Krishna Dhungana
[Metronidazole-induced esophageal ulcer. A case report].
January 1998, Revista de gastroenterologia de Mexico,
Copied contents to your clipboard!