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109 streptococcal strains, belonging to diverse serological groups and types, were investigated as regards their capacity to bind IgG aggregates in the presence of fresh serum. Strains capable of such binding were not found in groups B,C,D,E,G,L,M or N. Such binding was restricted to a few types of group A streptococci: the potentially nephritogenic types 2, 6 and 12, and four strains belonging to type M 39, M 46 and M 22 or M 62, the nephritogenic capacity of which is unknown. Two of five strains isolated from patients with acute post-stretococcal glomerulonephritis (AGN) and 19/28 type T 12, SOR-strains, isolated during an epidemic in a kindergarten with associated cases of AGN, were found to bind aggregates. The findings suggest a possible association between capacity to bind aggregates in the presence of serum and the serological types of group A streptococci involved in acute nephritis following pharyngeal infection.
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Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology,
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October 1979,
Acta pathologica et microbiologica Scandinavica. Section B, Microbiology,
P Christensen, and
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P Christensen, and
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P A Mårdh
March 1984,
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P Christensen, and
A G Sjöholm, and
S Holm, and
B Hovelius, and
P A Mårdh
January 1989,
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P Christensen, and
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P A Mårdh
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P Christensen, and
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S Holm, and
B Hovelius, and
P A Mårdh
June 1976,
Acta pathologica et microbiologica Scandinavica. Section C, Immunology,
