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Pulmonary artery blood flow velocity was measured in 15 dogs by a recently developed direct intraluminal pulsed Doppler technique. Changes in velocity characteristics under conditions of experimentally induced hypoxic pulmonary hypertension were observed. Experimental conditions (fractional inspired oxygen concentration = 0.10) produced significant increases in mean pulmonary artery pressure and pulmonary vascular resistance. Overall and maximal negative velocity increased with pulmonary hypertension. Negative velocity occurred predominantly in the posterior half of the pulmonary artery during both control and experimental conditions. With pulmonary hypertension, diastolic negative velocity increased only in the posterior half of the pulmonary artery and systolic negative velocity decreased only in the anterior half. More basic knowledge of pulmonary artery blood flow characteristics may facilitate an informed approach to noninvasive detection of pulmonary hypertension. Direct measurements by this recently developed intraluminal technique will be useful in studying various conditions with altered pulmonary blood flow.
E G Frantz, and
G W Henry, and
C L Lucas, and
B A Keagy, and
M E Lores, and
E Criado, and
J I Ferreiro, and
B R Wilcox
July 2012,
Canadian journal of anaesthesia = Journal canadien d'anesthesie,
E G Frantz, and
G W Henry, and
C L Lucas, and
B A Keagy, and
M E Lores, and
E Criado, and
J I Ferreiro, and
B R Wilcox
December 2021,
The Knee,
E G Frantz, and
G W Henry, and
C L Lucas, and
B A Keagy, and
M E Lores, and
E Criado, and
J I Ferreiro, and
B R Wilcox
September 2003,
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology,
E G Frantz, and
G W Henry, and
C L Lucas, and
B A Keagy, and
M E Lores, and
E Criado, and
J I Ferreiro, and
B R Wilcox
September 1995,
Archives of disease in childhood. Fetal and neonatal edition,
E G Frantz, and
G W Henry, and
C L Lucas, and
B A Keagy, and
M E Lores, and
E Criado, and
J I Ferreiro, and
B R Wilcox
October 1984,
Cardiovascular research,
E G Frantz, and
G W Henry, and
C L Lucas, and
B A Keagy, and
M E Lores, and
E Criado, and
J I Ferreiro, and
B R Wilcox
February 1990,
Journal of applied physiology (Bethesda, Md. : 1985),
E G Frantz, and
G W Henry, and
C L Lucas, and
B A Keagy, and
M E Lores, and
E Criado, and
J I Ferreiro, and
B R Wilcox
July 1974,
The Journal of physiology,
E G Frantz, and
G W Henry, and
C L Lucas, and
B A Keagy, and
M E Lores, and
E Criado, and
J I Ferreiro, and
B R Wilcox
August 2012,
Early human development,
E G Frantz, and
G W Henry, and
C L Lucas, and
B A Keagy, and
M E Lores, and
E Criado, and
J I Ferreiro, and
B R Wilcox
May 1979,
Respiration physiology,
E G Frantz, and
G W Henry, and
C L Lucas, and
B A Keagy, and
M E Lores, and
E Criado, and
J I Ferreiro, and
B R Wilcox
January 1996,
Gynecologic and obstetric investigation,
