Biomaterial Database

Continuous-wave versus range-gated pulsed Doppler power frequency spectrum analysis in the detection of carotid arterial occlusive disease. 1986

T R Harward, and E F Bernstein, and A Fronek

Two types of ultrasonic Doppler velocity metering devices currently used in the detection of extracranial carotid artery disease, the continuous-wave (CW) and the range-gated pulsed (RP) Doppler systems, were compared in the present study. Power frequency spectrum analysis (PFSA) was performed on 130 carotid arterial bifurcations with a CW Doppler and 81 carotid arteries with an RP Doppler system. All results were compared with angiographic findings. The frequency bandwidth at 50% peak power (f50%), a quantitative index for defining spectral broadening, detected stenoses equal to or greater than 50% diameter reduction with 93% sensitivity, 92% specificity, and 92% accuracy with the CW system. With the RP Doppler, the same degree of stenosis was identified with 94% sensitivity, 93% specificity, and 93% accuracy. Compared with angiographic classification into 0-24%, 25-49%, and 50-99% diameter reduction categories, CW Doppler PFSA and an 85% overall accuracy, and the RP Doppler overall accuracy was 86%. CW Doppler also correctly identified 15 of 16 internal carotid artery (ICA) occlusions; 8 of 8 ICA occlusions were correctly identified with the RP Doppler. Thus, both techniques detected carotid artery disease with comparable results. For research and ease of operation, an RP Doppler system with a variable sampling volume appears to be most desirable. However, a standard CW system is superior if utility and cost-effectiveness are of prime importance.

UI	MeSH Term	Description	Entries
D002340	Carotid Artery Diseases	Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.	Carotid Atherosclerosis,Common Carotid Artery Disease,Internal Carotid Artery Disease,Arterial Diseases, Carotid,Arterial Diseases, Common Carotid,Arterial Diseases, External Carotid,Arterial Diseases, Internal Carotid,Atherosclerotic Disease, Carotid,Carotid Artery Disorders,Carotid Atherosclerotic Disease,Common Carotid Artery Diseases,External Carotid Artery Diseases,Internal Carotid Artery Diseases,Arterial Disease, Carotid,Artery Disease, Carotid,Artery Diseases, Carotid,Artery Disorder, Carotid,Artery Disorders, Carotid,Atherosclerotic Diseases, Carotid,Carotid Arterial Disease,Carotid Arterial Diseases,Carotid Artery Disease,Carotid Artery Disorder,Carotid Atheroscleroses,Carotid Atherosclerotic Diseases,Disorders, Carotid Artery
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001157	Arterial Occlusive Diseases	Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.	Arterial Obstructive Diseases,Arterial Occlusion,Arterial Obstructive Disease,Arterial Occlusions,Arterial Occlusive Disease,Disease, Arterial Obstructive,Disease, Arterial Occlusive,Obstructive Disease, Arterial,Occlusion, Arterial,Occlusive Disease, Arterial
D014463	Ultrasonography	The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.	Echography,Echotomography,Echotomography, Computer,Sonography, Medical,Tomography, Ultrasonic,Ultrasonic Diagnosis,Ultrasonic Imaging,Ultrasonographic Imaging,Computer Echotomography,Diagnosis, Ultrasonic,Diagnostic Ultrasound,Ultrasonic Tomography,Ultrasound Imaging,Diagnoses, Ultrasonic,Diagnostic Ultrasounds,Imaging, Ultrasonic,Imaging, Ultrasonographic,Imaging, Ultrasound,Imagings, Ultrasonographic,Imagings, Ultrasound,Medical Sonography,Ultrasonic Diagnoses,Ultrasonographic Imagings,Ultrasound, Diagnostic,Ultrasounds, Diagnostic
D014465	Ultrasonics	A subfield of acoustics dealing in the radio frequency range higher than acoustic SOUND waves (approximately above 20 kilohertz). Ultrasonic radiation is used therapeutically (DIATHERMY and ULTRASONIC THERAPY) to generate HEAT and to selectively destroy tissues. It is also used in diagnostics, for example, ULTRASONOGRAPHY; ECHOENCEPHALOGRAPHY; and ECHOCARDIOGRAPHY, to visually display echoes received from irradiated tissues.	Ultrasonic