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The efficacy of domperidone 20 mg, droperidol 2.5 mg, metoclopramide 10 mg or placebo (saline) administered i.v. before induction of anaesthesia, was studied in 199 women undergoing gynaecological surgery as day cases. Following a standardized general anaesthetic technique, droperidol or metoclopramide significantly reduced the incidence of nausea and vomiting; domperidone decreased the incidence of postoperative nausea alone. The occurrence of extrapyramidal reactions was similar in all groups. Patients treated with antiemetics were no more sedated than those given placebo. Those receiving droperidol complained of significantly less postoperative pain than those who had received domperidone or metoclopramide.
T H Madej, and
K H Simpson
May 1995,
Anaesthesia,
T H Madej, and
K H Simpson
November 1991,
Masui. The Japanese journal of anesthesiology,
T H Madej, and
K H Simpson
January 1979,
Anesthesia and analgesia,
T H Madej, and
K H Simpson
June 1983,
Ugeskrift for laeger,
T H Madej, and
K H Simpson
January 2002,
Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat,
T H Madej, and
K H Simpson
December 2003,
Canadian journal of anaesthesia = Journal canadien d'anesthesie,
T H Madej, and
K H Simpson
September 1996,
European journal of anaesthesiology,
T H Madej, and
K H Simpson
February 1998,
Acta anaesthesiologica Scandinavica,
T H Madej, and
K H Simpson
February 1996,
Canadian journal of anaesthesia = Journal canadien d'anesthesie,
T H Madej, and
K H Simpson
January 2011,
Gynecologic and obstetric investigation,
