-transparent.png){kind=logo}
The biocompatibility of vitreous carbon and carbon fibre reinforced carbon (CFRC) as middle ear implants was investigated. In separate animal model systems, vitreous carbon was implanted in the middle ear of 20 DA rats for up to 6 months, whilst 3 varieties of CFRC (basic or crude, ultrasonically cleaned, glazed) were implanted in 98 guinea-pig middle ears for up to 4 months. Tissue reactions to implantation were assessed by means of stereoscopic and standard light microscopy, and scanning electron microscopy with chemical analysis facilities (EDAX, WDAX). Vitreous carbon and glazed CFRC were considered suitable for human implantation and a trial of the latter was started in 23 patients (14 partial, 9 total ossicular implants). At 9 months, only 52% of the implants were still in situ; 40% had been extruded and 8% had elicited inflammatory responses which would undoubtedly result in extrusion. Carbon particle dissemination with carbon fibre destruction and exposure as a result of peroperative prosthesis drilling were considered the likely causes for the failure of this implant.
A W Blayney, and
J A Romero Rio, and
K R Williams, and
A Guilhaume, and
M Bagot D'Arc, and
M Portmann
September 1988,
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery,
A W Blayney, and
J A Romero Rio, and
K R Williams, and
A Guilhaume, and
M Bagot D'Arc, and
M Portmann
June 2010,
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,
A W Blayney, and
J A Romero Rio, and
K R Williams, and
A Guilhaume, and
M Bagot D'Arc, and
M Portmann
December 1988,
Ceskoslovenska otolaryngologie,
A W Blayney, and
J A Romero Rio, and
K R Williams, and
A Guilhaume, and
M Bagot D'Arc, and
M Portmann
July 1993,
Laryngo- rhino- otologie,
A W Blayney, and
J A Romero Rio, and
K R Williams, and
A Guilhaume, and
M Bagot D'Arc, and
M Portmann
August 1978,
Clinical otolaryngology and allied sciences,
A W Blayney, and
J A Romero Rio, and
K R Williams, and
A Guilhaume, and
M Bagot D'Arc, and
M Portmann
December 1948,
The Annals of otology, rhinology, and laryngology,
A W Blayney, and
J A Romero Rio, and
K R Williams, and
A Guilhaume, and
M Bagot D'Arc, and
M Portmann
January 1981,
Revue de laryngologie - otologie - rhinologie,
A W Blayney, and
J A Romero Rio, and
K R Williams, and
A Guilhaume, and
M Bagot D'Arc, and
M Portmann
January 1986,
The Annals of otology, rhinology, and laryngology,
A W Blayney, and
J A Romero Rio, and
K R Williams, and
A Guilhaume, and
M Bagot D'Arc, and
M Portmann
April 1953,
The Laryngoscope,
A W Blayney, and
J A Romero Rio, and
K R Williams, and
A Guilhaume, and
M Bagot D'Arc, and
M Portmann
January 1953,
Transactions of the American Laryngological, Rhinological and Otological Society, Inc,
