Dialysis-related amyloid is amyloid of beta-2-microglobulin (AM beta 2M) origin.
1986
T T Casey, and
W J Stone, and
C R DiRaimondo, and
D L Page, and
P D Gorevic
UI
MeSH Term
Description
Entries
D006435
Renal Dialysis
Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000682
Amyloid
A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.
An 11-kDa protein associated with the outer membrane of many cells including LYMPHOCYTES. It is the small subunit of MHC CLASS I MOLECULES. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, CEREBROSPINAL FLUID, and urine of healthy individuals, and to a much greater degree in the urine and plasma of patients with tubular PROTEINURIA, renal failure, or kidney transplants.
Thymotaxin,beta 2 Microglobulin
Related Publications
T T Casey, and
W J Stone, and
C R DiRaimondo, and
D L Page, and
P D Gorevic